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574 articles

Checkpoint Immunotherapy Targets CDK12-Mutant Metastatic Cancers in Phase 2 Trial
Cancer Research

Checkpoint Immunotherapy Targets CDK12-Mutant Metastatic Cancers in Phase 2 Trial

A completed Phase 2 trial tests nivolumab plus ipilimumab in CDK12-mutant metastatic prostate and solid tumors across 56 patients.

Essai clinique
9 mai 2026 0
CBT Smartphone App Tested Against Active Placebo for Moderate Depression
Brain Health

CBT Smartphone App Tested Against Active Placebo for Moderate Depression

A completed RCT tested whether a CBT-based smartphone app reduces moderate depression versus an active placebo in 158 participants; outcomes are not reported in the registration record.

Essai clinique
9 mai 2026 0
AI Robots Deliver Cognitive Tests at Home for Alzheimer's and MCI Patients
Brain Health

AI Robots Deliver Cognitive Tests at Home for Alzheimer's and MCI Patients

A completed pilot trial tested humanoid robots and AI predictive models to manage dementia care at home, personalizing treatment pathways.

Essai clinique
9 mai 2026 0
Fisetin Tested as Senolytic Treatment to Reduce COVID-19 Complications
Longevity & Aging

Fisetin Tested as Senolytic Treatment to Reduce COVID-19 Complications

A Phase 2 pilot trial investigates whether the natural senolytic compound fisetin can reduce dysfunction and complications in COVID-19 patients.

Essai clinique
8 mai 2026 0
NAD Precursor Combo Tested to Boost Muscle Mitochondria in Elderly Adults
Metabolic Health

NAD Precursor Combo Tested to Boost Muscle Mitochondria in Elderly Adults

Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.

Essai clinique
8 mai 2026 0
Single vs Double Bevacizumab Injections Compared for Macular Degeneration Treatment
Brain Health

Single vs Double Bevacizumab Injections Compared for Macular Degeneration Treatment

A Phase 4 RCT tests whether one bevacizumab injection matches two combined doses for neovascular AMD outcomes over 12 months.

Essai clinique
8 mai 2026 0
Aquatic Exercise Lowers Blood Pressure and Boosts Health in Older Adults
Exercise & Fitness

Aquatic Exercise Lowers Blood Pressure and Boosts Health in Older Adults

A completed RCT tests how water-based exercise at varying intensities affects blood pressure, sleep, mood, and function in elderly participants.

Essai clinique
8 mai 2026 0
Online Sleep Therapy Targets Alcohol Use in Heavy Drinkers with Insomnia
Sleep & Recovery

Online Sleep Therapy Targets Alcohol Use in Heavy Drinkers with Insomnia

A completed trial tests whether internet-based CBT-I can reduce both insomnia severity and alcohol consumption in heavy-drinking adults.

Essai clinique
8 mai 2026 0
Copenhagen Trial Pits Exercise, Fasting, and NR Against Each Other to Slow Aging
Longevity & Aging

Copenhagen Trial Pits Exercise, Fasting, and NR Against Each Other to Slow Aging

A completed RCT from the University of Copenhagen tests whether aerobic exercise, time-restricted feeding, or NR supplementation best improves biological aging markers in healthy older adults.

Essai clinique
7 mai 2026 0
HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial
Cancer Research

HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial

A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.

Essai clinique
7 mai 2026 0
Low-Dose Ipilimumab Plus Pembrolizumab Targets Melanoma Brain Metastases
Cancer Research

Low-Dose Ipilimumab Plus Pembrolizumab Targets Melanoma Brain Metastases

A completed Phase II trial tests whether combining two checkpoint inhibitors can safely and effectively treat melanoma that has spread to the brain.

Essai clinique
7 mai 2026 0
Bioavailable Turmeric Supplement Tested Against Cognitive Decline in Metabolic Syndrome
Brain Health

Bioavailable Turmeric Supplement Tested Against Cognitive Decline in Metabolic Syndrome

The EPICURO trial tests MERIVA® turmeric over 6 months to see if it protects cognition in adults with metabolic syndrome.

Essai clinique
7 mai 2026 0
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