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How Gut Bacteria and Senescent Cells Team Up to Drive Age-Related Disease
Gut & Microbiome

How Gut Bacteria and Senescent Cells Team Up to Drive Age-Related Disease

A new review maps the bidirectional crosstalk between gut microbiota and cellular senescence driving multi-organ degeneration.

Synthèse
3 mai 2026 0
Afternoon Heart Surgery May Reduce Muscle Injury But Evidence Remains Thin
Heart Health

Afternoon Heart Surgery May Reduce Muscle Injury But Evidence Remains Thin

A Cochrane review finds only one small RCT on surgical timing for cardiac surgery, with afternoon starts linked to lower troponin release.

Synthèse
2 mai 2026 0
Senolytics Ranked: Fisetin and Quercetin Lead Evidence-Based Longevity Stacks
Supplements

Senolytics Ranked: Fisetin and Quercetin Lead Evidence-Based Longevity Stacks

Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks.

Synthèse
1 mai 2026 0
Liver Support Systems Show No Clear Survival Benefit in Acute Liver Failure
Metabolic Health

Liver Support Systems Show No Clear Survival Benefit in Acute Liver Failure

A Cochrane meta-analysis of 11 RCTs finds very low-certainty evidence that liver support systems neither reduce mortality nor improve key outcomes in ALF.

Synthèse
1 mai 2026 0
Digital Twins Could Revolutionize How IBD Clinical Trials Are Run
Autoimmune & Arthritis

Digital Twins Could Revolutionize How IBD Clinical Trials Are Run

Virtual patient replicas built from multimodal data may slash trial costs, generate synthetic control arms, and predict treatment response in IBD.

Synthèse
30 avr. 2026 0
Vitamin D Supplements Show Only Modest Benefit Against Respiratory Infections in Young Children
Supplements

Vitamin D Supplements Show Only Modest Benefit Against Respiratory Infections in Young Children

A Cochrane review of 107 RCTs finds vitamin D may slightly cut ARI-related doctor visits in under-5s, but evidence remains low-certainty.

Synthèse
29 avr. 2026 0
DNA Mutation Clocks Reveal How Aging Drives Cancer Risk From Within
Cancer Research

DNA Mutation Clocks Reveal How Aging Drives Cancer Risk From Within

Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.

Synthèse
29 avr. 2026 0
Why Alzheimer's and Parkinson's Share a Protein Misfolding Network
Brain Health

Why Alzheimer's and Parkinson's Share a Protein Misfolding Network

A landmark review argues neurodegeneration is driven by interacting misfolded proteins, not single culprits — reshaping diagnosis and treatment.

Synthèse
29 avr. 2026 0
How Normal Aging Quietly Destroys Your Lungs Before Disease Strikes
Longevity & Aging

How Normal Aging Quietly Destroys Your Lungs Before Disease Strikes

A landmark review maps the structural, genetic, and molecular changes that erode lung function with age — and why reversing them matters.

Synthèse
29 avr. 2026 0
How Aging T Cells Drive Chronic Skin Inflammation and What Can Stop Them
Autoimmune & Arthritis

How Aging T Cells Drive Chronic Skin Inflammation and What Can Stop Them

Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.

Synthèse
29 avr. 2026 0
Centenarians Defy Immune Aging Through Unique Inflammatory Control Mechanisms
Longevity & Aging

Centenarians Defy Immune Aging Through Unique Inflammatory Control Mechanisms

New research reveals how people over 100 maintain youthful immune systems despite chronic inflammation, offering insights for healthy aging.

Synthèse
28 avr. 2026 0
Longevity Supplement Stacks Ranked by Evidence: Fisetin, Quercetin, Resveratrol and Spermidine
Supplements

Longevity Supplement Stacks Ranked by Evidence: Fisetin, Quercetin, Resveratrol and Spermidine

A product review breaks down the evidence tiers for four popular longevity supplements and rates the best commercial stacks.

Synthèse
27 avr. 2026 0
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