Autoimmune disorders, rheumatoid arthritis, systemic inflammation, and immune dysregulation
303 articles
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
Maîtrisez l'architecture moléculaire de la dérégulation du complément dans le vieillissement — de la biochimie des protéines régulatrices aux cibles thérapeutiques de pointe — et comprenez comment des interventions de précision peuvent rétablir l'équilibre sans démanteler l'immunité.
Allez au-delà des bases pour explorer comment les voies du complément, les défaillances régulatrices et les cellules sénescentes interagissent pour alimenter l'inflammation chronique qui accélère le vieillissement au niveau moléculaire.
Découvrez comment un bras caché de votre système immunitaire, appelé le système du complément, alimente silencieusement l'inflammation chronique associée au vieillissement — et ce que vous pouvez faire pour y remédier.
A Phase 2 trial testing rituximab, infliximab, and tocilizumab for hard-to-treat non-ANCA vasculitis was terminated before completion.
A multi-biomarker study finds pwMS show accelerated thymic involution, senescent T cell expansion, and neuroinflammation linked to aging.
A comparative protein interaction map of SARS-CoV-2 and its bat progenitor uncovers the molecular switch behind immune evasion and species barriers.
A newly identified immune axis involving CD16+ γδ T cells and antibody-dependent killing may reshape how we understand HBV immune control.
A cluster randomized trial tests whether couples counseling plus stigma workshops can boost PrEP/ART uptake among young South African adults.
A landmark 48-RCT Cochrane review finds high-certainty evidence that convalescent plasma does not reduce death in moderate-to-severe COVID-19.
A runaway immune response — not the pathogen itself — drives citrus greening disease, echoing autoimmune mechanisms seen in human illness.
A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.
