Autoimmune disorders, rheumatoid arthritis, systemic inflammation, and immune dysregulation
303 articles
Un essai de phase 4 examine si la simplification du traitement du VIH à deux médicaments aggrave la réplication virale latente et le dysfonctionnement immunitaire.
Un essai de phase 3 complété a évalué si le biologique anti-TNF infliximab traite de manière sûre et efficace le psoriasis en plaques.
Un essai de phase 1/2 évalue un candidat vaccin double RSV/hMPV chez des adultes âgés, ciblant deux menaces respiratoires majeures en une seule injection.
Des chercheurs détournent la technologie mRNA-lipid nanoparticle pour prévenir et traiter l'asthme allergique chez la souris, obtenant une réduction d'environ 100 fois du nombre d'éosinophiles dans les voies respiratoires.
A major review outlines how targeted hematologic therapies are transforming outcomes in MGRS, a rare but serious cause of kidney injury.
A landmark Phase I trial of 108 adults tested the first adenovirus-vectored COVID-19 vaccine for safety and immune response.
A completed RCT tests whether 1-hour pathogen detection paired with antimicrobial stewardship slashes broad-spectrum antibiotic days in HAP patients.
A new WHO public health emergency declaration over Bundibugyo Ebola raises urgent questions about health equity and international pandemic preparedness.
Scientists used CRISPR to find SPART, a human gene that restricts a whole family of dangerous flaviviruses including Zika and dengue.
A massive measles outbreak in Bangladesh exposes the deadly consequences of declining vaccination rates worldwide.
A rare and deadly hantavirus infected passengers on a cruise ship, raising urgent questions about containment at sea.
A newly identified protein, SCARF2, acts as an internal escort for HBV, transporting the virus from the cytoplasm to the nuclear pore — a potential new drug target.
