Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
886 articles
Resting-state EEG slow waves predict amyloid buildup and neurodegeneration in cognitively normal older adults, offering a non-invasive early warning tool.
Genetic variants in the water channel gene AQP4 directly affect brain volume and cognition — and interact with sleep to accelerate Alzheimer's progression.
New research shows caffeine selectively restores a brain circuit for social memory damaged by sleep loss, without overstimulating healthy neurons.
New research in Cell maps the fronto-insular circuits behind accelerated TMS, potentially transforming rapid depression treatment.
New spatiotemporal mapping of the human meninges exposes how immune cells and brain barriers co-develop from 6–23 gestational weeks.
A new genetic tracing system reveals the brain's waste-clearance routes are compartmentalized, rapid in some areas, and disrupted differently by inflammation vs. amyloid.
A neuron-specific proteasome system governs tau pathology, with APOE4 carriers showing heightened vulnerability as this system declines with age.
A new Nature Neuroscience study reveals an unexpected molecular mechanism that initiates tau aggregation, the hallmark of Alzheimer's disease.
Cambridge researchers found a gene network that shuts off nerve repair — and an existing hormone drug that reactivates it.
Scientists built human amygdala-like brain organoids that model stress circuitry, uncovering a novel cortisol-driven mechanism tied to primate-specific gene regulation.
Researchers at Duke University tested a blood-based biomarker to stratify Alzheimer's patients from healthy adults, aiming to enable earlier detection.
Sarah Ann Macklin and Simon Hill explore how relentless health optimization creates anxiety, perfectionism, and a broken relationship with your own body.
