FDA Approves Baxfendy, a New Aldosterone Synthase Inhibitor for Hypertension
Baxdrostat becomes the first-in-class aldosterone synthase inhibitor approved to treat resistant hypertension alongside existing drugs.
Insulin resistance, blood sugar regulation, metabolic syndrome, and body composition
409 articles
Baxdrostat becomes the first-in-class aldosterone synthase inhibitor approved to treat resistant hypertension alongside existing drugs.
Allez au-delà des notions fondamentales et explorez les mécanismes biochimiques de la glycation — de la cascade de la réaction de Maillard à la signalisation RAGE et aux pontages tissulaires — pour comprendre pourquoi les AGEs sont au cœur du vieillissement et des maladies métaboliques.
Découvrez comment les molécules de sucre endommagent silencieusement vos protéines et vos cellules au fil du temps — et ce que vous pouvez faire pour ralentir ce processus de vieillissement sournois.
FDA approval of the first T1D delay drug nearly doubled islet autoantibody testing, but critical gaps remain in screening healthy children.
A new review links feline age-related obesity to SASP-driven chronic inflammation, offering translational insights for human metabolic disease.
The triple agonist retatrutide drives deep metabolic shifts beyond weight loss, improving key biomarkers of cardiovascular and insulin health.
Scientists identify IL-11 as a molecular brake on beige fat thermogenesis, and show blocking it improves metabolism in obese mice.
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
Three new NIH-funded findings tackle metabolic aging, cardiovascular risk, and a surprising hormonal brake on brain tumors.
A Cochrane review of 37 RCTs finds obesity drugs modestly reduce weight in adolescents, but evidence quality is low and long-term data are absent.
A rigorous MRI-based study finds that repeated hypoglycemia episodes leave brain glucose transport kinetics unchanged, challenging a leading hypothesis.
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.