Autoimmune diseases, immune modulation, inflammation, and self-tolerance
219 articles
New review reveals how immune cells orchestrate tissue scarring across organs, offering therapeutic targets for fibrosis affecting nearly a billion people.
New research reveals how lactate triggers lactylation, an epigenetic modification that fuels rheumatoid arthritis and lupus progression.
Natural flavonoid fisetin activates mitophagy and xenophagy pathways to restrict intracellular Salmonella growth in immune cells.
Study reveals how gut microbes transform T cells into potent autoimmune drivers that migrate to joints and promote arthritis.
New research reveals how a mitochondrial enzyme enhances immune cell function to fight bacterial lung infections and reduce inflammation.
New research reveals how immune cells use cysteine for both antioxidant defense and energy production, with major implications for cancer treatment.
Engineered immune cells offer new hope for treating kidney diseases that resist standard therapies, potentially improving long-term health outcomes.
Combining targeted therapies may help patients with severe hidradenitis suppurativa who don't respond to standard treatments.
New targeted therapies and biomarker-driven approaches are revolutionizing RA management, potentially improving healthspan for millions.
New research reveals how rheumatoid arthritis dramatically increases kidney disease risk through inflammation and medication effects.
New research reveals how KLF2 and KLF3 proteins regulate T cell movement and exhaustion, offering insights for immune system optimization.
New research reveals how tissue fibroblasts orchestrate age-related inflammation, creating exhausted T cells that increase vulnerability to disease.
