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Auto-immunité

Autoimmune diseases, immune modulation, inflammation, and self-tolerance

219 articles

New Oral Psoriasis Drug Icotrokinra Outperforms Existing Treatment in Phase 3 Trials
Autoimmune & Arthritis

New Oral Psoriasis Drug Icotrokinra Outperforms Existing Treatment in Phase 3 Trials

Oral peptide targeting IL-23 receptor shows superior efficacy vs placebo and deucravacitinib in moderate-to-severe plaque psoriasis.

Article de recherche
8 avr. 2026 0
New Oral Drug Icotrokinra Shows Promise for Plaque Psoriasis Treatment
Autoimmune & Arthritis

New Oral Drug Icotrokinra Shows Promise for Plaque Psoriasis Treatment

Clinical trial results for oral icotrokinra in treating plaque psoriasis across adult and adolescent patients published in NEJM.

Article de recherche
7 avr. 2026 0
Atopic Dermatitis Has Distinct Immune Subtypes That Require Different Treatments
Autoimmune & Arthritis

Atopic Dermatitis Has Distinct Immune Subtypes That Require Different Treatments

New research reveals atopic dermatitis has multiple biological subtypes, each requiring personalized treatment approaches.

Article de recherche
5 avr. 2026 0
Spatial Mapping Reveals How Fibroblasts and Macrophages Drive Systemic Sclerosis
Autoimmune & Arthritis

Spatial Mapping Reveals How Fibroblasts and Macrophages Drive Systemic Sclerosis

New spatial multiomics study maps cellular interactions in systemic sclerosis, revealing fibroblast-macrophage dynamics.

Article de recherche
5 avr. 2026 0
IL-35 Blocks Neutrophil Traps to Reduce Smoking-Related Asthma Inflammation
Autoimmune & Arthritis

IL-35 Blocks Neutrophil Traps to Reduce Smoking-Related Asthma Inflammation

New research reveals how IL-35 therapy prevents neutrophil trap formation, offering hope for cigarette smoke-worsened asthma.

Article de recherche
5 avr. 2026 0
Calcineurin Inhibitors Show Promise for Autoimmune Diseases Despite Toxicity Risks
Autoimmune & Arthritis

Calcineurin Inhibitors Show Promise for Autoimmune Diseases Despite Toxicity Risks

Review examines immunosuppressive drugs like cyclosporine and tacrolimus, highlighting new applications and safety management strategies.

Article de recherche
4 avr. 2026 0
RNA Modification Protein IGF2BP3 Drives Joint Destruction in Rheumatoid Arthritis
Autoimmune & Arthritis

RNA Modification Protein IGF2BP3 Drives Joint Destruction in Rheumatoid Arthritis

New research reveals how IGF2BP3 protein promotes inflammation and tissue damage in rheumatoid arthritis through RNA modifications.

Article de recherche
4 avr. 2026 0
New Insights into Pemphigus Foliaceus Autoimmune Skin Disease
Autoimmune & Arthritis

New Insights into Pemphigus Foliaceus Autoimmune Skin Disease

Expert commentary on pemphigus foliaceus, a rare autoimmune blistering disease affecting skin health and immune function.

Article de recherche
4 avr. 2026 0
Italian MS Experts Reach Consensus on Personalized Multiple Sclerosis Treatment
Autoimmune & Arthritis

Italian MS Experts Reach Consensus on Personalized Multiple Sclerosis Treatment

Delphi study of 166 Italian neurologists establishes guidelines for individualized MS therapy based on patient needs and drug characteristics.

Article de recherche
3 avr. 2026 0
Italian MS Experts Reach Consensus on Early High-Efficacy Treatment Strategies
Autoimmune & Arthritis

Italian MS Experts Reach Consensus on Early High-Efficacy Treatment Strategies

65 neurologists from 54 Italian MS centers agree on when and how to use high-efficacy therapies to prevent irreversible disability.

Article de recherche
3 avr. 2026 0
Cell Death Protein MLKL Triggers Inflammation Through Mitochondrial DNA Release
Autoimmune & Arthritis

Cell Death Protein MLKL Triggers Inflammation Through Mitochondrial DNA Release

New research reveals how necroptosis activates immune pathways, offering targets for inflammatory bowel disease treatment.

Article de recherche
3 avr. 2026 0
Multi-Omics Integration Reveals New Psoriasis Research Pathways
Autoimmune & Arthritis

Multi-Omics Integration Reveals New Psoriasis Research Pathways

Comprehensive review explores how combining genomics, proteomics, and metabolomics advances psoriasis understanding and treatment.

Article de recherche
3 avr. 2026 0
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