Cancer Research
Telomerase Vaccine Plus Checkpoint Blockade Targets HPV-Driven Cancers
A completed Phase 2 trial tests UCPVax cancer vaccine combined with atezolizumab in cervical, anal, and head-and-neck cancers.
Essai clinique
10 mai 2026 0
Sujet
Cancer
Latest breakthroughs in cancer research, treatment, and prevention
602 articles
Cancer Research
Colonoscopy's Cancer Prevention Value Gets a Critical Reassessment
A Lancet commentary reexamines the true preventive benefit of colonoscopy screening, challenging assumptions about how we calculate cancer risk reduction.
Article de recherche
10 mai 2026 0
Cancer Research
Triple Combo Therapy Targets Chemo-Resistant Colorectal Cancer in Phase I Trial
A completed phase I trial tests regorafenib plus dual checkpoint inhibitors in 39 patients with hard-to-treat metastatic colorectal cancer.
Essai clinique
9 mai 2026 0
Cancer Research
Checkpoint Immunotherapy Targets CDK12-Mutant Metastatic Cancers in Phase 2 Trial
A completed Phase 2 trial tests nivolumab plus ipilimumab in CDK12-mutant metastatic prostate and solid tumors across 56 patients.
Essai clinique
9 mai 2026 0
Cancer Research
Cancer Stem Cells Use Tiny Vesicles to Shield Tumors from Immune Attack
A novel immune-evasion mechanism in triple-negative breast cancer reveals how cancer stem cells suppress anti-tumor immunity via extracellular vesicles.
Article de recherche
9 mai 2026 0
Cancer Research
New Immunotherapy Combo Achieves Durable Remissions in Treatment-Resistant Pancreatic Cancer
A triple immunotherapy unlocks anti-tumor CD4+ T cells — not CD8+ — to clear pancreatic tumors in mice, reshaping the immunotherapy playbook.
Article de recherche
9 mai 2026 0
Cancer Research
Long-Term Randomized Data Reveals Cumulative Urinary Toxicity Risks After Prostate Radiation
High-level randomized evidence quantifies genitourinary toxicity burden over time following prostate radiotherapy, with direct implications for treatment decisions.
Article de recherche
9 mai 2026 0
Cancer Research
Dual EGFR-TGFβ Blockade Achieves 54% Response Rate in Hard-to-Treat Head and Neck Cancer
Ficerafusp alfa plus pembrolizumab shows striking results in HPV-negative head and neck cancer, a notoriously difficult-to-treat population.
Article de recherche
9 mai 2026 0
Cancer Research
Four Leukemic Stem Cell Subtypes Explain Venetoclax Resistance in AML
Researchers identify four LSC subtypes that predict venetoclax resistance and reveal matched subtype-specific therapies for AML patients.
Article de recherche
9 mai 2026 0
Cancer Research
AI Radiomics May Detect Pancreatic Cancer Before It Becomes Visible
A new editorial in Gut explores how AI-powered radiomic analysis could identify occult pancreatic cancer missed by standard imaging.
Article de recherche
9 mai 2026 0
Cancer Research
Single Colonoscopy Cuts Colorectal Cancer Risk 19% Over 13 Years But Misses Mortality Target
The landmark NordICC trial's 13-year data shows one colonoscopy meaningfully reduces cancer incidence but doesn't significantly lower mortality.
Article de recherche
9 mai 2026 0
Cancer Research
Hidden Blood-Brain Barrier in Lung Cancer Blocks Immunotherapy From Working
Researchers discover a BBB-like vascular shield in small cell lung cancer that blocks immune cells — and find a drug combo to overcome it.
Article de recherche
9 mai 2026 0