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Cancer

Latest breakthroughs in cancer research, treatment, and prevention

602 articles

New Strategies Finally Target Cancer's 'Undruggable' Proteins
Cancer Research

New Strategies Finally Target Cancer's 'Undruggable' Proteins

Long-elusive cancer-driving proteins are yielding to innovative drug strategies, opening new frontiers in oncology treatment.

Article de recherche
9 mai 2026 0
Neurons Donate Mitochondria to Cancer Cells to Fuel Metastasis
Cancer Research

Neurons Donate Mitochondria to Cancer Cells to Fuel Metastasis

A Nature study reveals neurons physically transfer mitochondria to breast cancer cells via tunneling nanotubes, boosting metastatic potential.

Article de recherche
8 mai 2026 0
Rogue Cell State Fuels Colorectal Cancer Spread — and a Drug Can Reverse It
Cancer Research

Rogue Cell State Fuels Colorectal Cancer Spread — and a Drug Can Reverse It

A high-MAPK, low-WNT tumor cell state drives CRC metastasis, and blocking mutant KRAS suppresses it in mice.

Article de recherche
8 mai 2026 0
9-Week Immunotherapy Before Surgery Keeps Colon Cancer Patients Relapse-Free for 3 Years
Cancer Research

9-Week Immunotherapy Before Surgery Keeps Colon Cancer Patients Relapse-Free for 3 Years

A short pre-surgery course of pembrolizumab left zero relapses in colorectal cancer patients after 33 months — reshaping treatment strategy.

Communiqué de presse
7 mai 2026 0
Senolytics Fail to Protect Bone From Chemotherapy-Induced Loss
Cancer Research

Senolytics Fail to Protect Bone From Chemotherapy-Induced Loss

A mouse study finds that senolytic drugs cannot prevent chemotherapy-driven bone loss, challenging a leading hypothesis about its cause.

Article de recherche
7 mai 2026 0
Ferroptosis Emerges as a Targetable Vulnerability in Deadly Anaplastic Thyroid Cancer
Cancer Research

Ferroptosis Emerges as a Targetable Vulnerability in Deadly Anaplastic Thyroid Cancer

A comprehensive review reveals how iron-driven cell death can be exploited to treat ATC, one of the most lethal human cancers.

Article de recherche
7 mai 2026 0
HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial
Cancer Research

HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial

A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.

Essai clinique
7 mai 2026 0
Low-Dose Ipilimumab Plus Pembrolizumab Targets Melanoma Brain Metastases
Cancer Research

Low-Dose Ipilimumab Plus Pembrolizumab Targets Melanoma Brain Metastases

A completed Phase II trial tests whether combining two checkpoint inhibitors can safely and effectively treat melanoma that has spread to the brain.

Essai clinique
7 mai 2026 0
Nivolumab Patient Develops Rare Brain-to-Blood Bacterial Spread from Oral Microbe
Cancer Research

Nivolumab Patient Develops Rare Brain-to-Blood Bacterial Spread from Oral Microbe

A cancer patient on nivolumab developed Eikenella corrodens bacteremia after CNS infection, revealing how immune checkpoint therapy may enable dangerous microbial dissemination.

Article de recherche
6 mai 2026 0
FDA Grants Expanded Approval to Zongertinib for HER2-Mutant Lung Cancer
Cancer Research

FDA Grants Expanded Approval to Zongertinib for HER2-Mutant Lung Cancer

The FDA expanded accelerated approval for zongertinib in HER2-mutant NSCLC, marking a targeted therapy milestone for a hard-to-treat mutation.

Approbation de médicament
6 mai 2026 0
Stiff Breast Tissue Recruits Immune Cells That Damage DNA and Drive Cancer
Cancer Research

Stiff Breast Tissue Recruits Immune Cells That Damage DNA and Drive Cancer

Tissue stiffness triggers a chain reaction — recruiting macrophages that generate DNA-damaging lipid byproducts — linking fibrosis directly to cancer initiation.

Article de recherche
6 mai 2026 0
IL-6 Signaling Exposes a Metabolic Weak Spot in Bile Duct Cancer
Cancer Research

IL-6 Signaling Exposes a Metabolic Weak Spot in Bile Duct Cancer

Tumor cells in intrahepatic cholangiocarcinoma hijack IL-6 signaling to fuel growth — creating a targetable metabolic vulnerability.

Article de recherche
5 mai 2026 0
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