Fasting-Mimicking Diet Boosts Cellular Cleanup and Metabolic Health in Humans
New clinical trial shows fasting-mimicking diets enhance autophagy and improve glucose metabolism in healthy adults over just 6 days.
20 articles
New clinical trial shows fasting-mimicking diets enhance autophagy and improve glucose metabolism in healthy adults over just 6 days.
A randomised trial finds monthly 5-day fasting-mimicking diet cycles significantly reduce myocardial triglyceride content in type 2 diabetes patients.
A pilot trial shows a recipe-based FMD reduces body fat and IGF-1 while preserving muscle mass in breast cancer patients undergoing chemotherapy.
Un essai de 12 mois révèle qu'un régime mimant le jeûne réduit significativement la graisse viscérale et sous-cutanée abdominale tout en préservant la masse musculaire chez des patients atteints de diabète de type 2.
A randomized trial finds 5-day monthly fasting cycles dramatically improve Crohn's disease remission rates and reduce gut inflammation.
New review synthesizes preclinical and clinical evidence showing fasting may sensitize tumors to chemotherapy while protecting healthy cells.
Dr Valter Longo argues the 5-day fasting-mimicking diet triggers deep cellular repair — from autophagy peaks to tissue regeneration after refeeding.
A proteomics study tracking 3,000 blood proteins reveals fasting's deepest benefits emerge only after 72 hours without food.
Five-year study reveals how traditional Mediterranean eating patterns combined with periodic fasting affects weight and metabolic health.
Dr. Fung breaks down four distinct fasting approaches, including a surprising fourth type that involves consuming calories during extended fasts.
Mouse study shows FMD cycles dramatically reduce acute kidney injury and CKD progression by suppressing CCL2-driven monocyte infiltration.
Thomas DeLauer reveals unconventional methods to eliminate hunger during 16+ hour fasts using temperature, texture, and neurological triggers.
A 42-woman trial shows 5-day fasting cuts leptin, insulin, and glucose while boosting ketones and mood—but psychology shapes outcomes.
Un régime mimant le jeûne active la sécrétion d'IFNβ dans les macrophages tumoraux en dégradant le suppresseur immunitaire Trex1 via une voie du protéasome pilotée par NRF1.
Une revue intégrative de 2025 montre que les régimes méditerranéen, à base de plantes et les régimes de jeûne réduisent la stéatose hépatique et le dysfonctionnement métabolique chez les patients atteints de MASLD.
Dr. Jamnadas explains how metabolic flexibility through fasting helps your body switch from glucose to fat-burning ketones.
Dr. Jamnadas explains the metabolic magic of 36-hour fasts and provides a step-by-step progression from skipping meals to multi-day fasts.
Extended fasting activates powerful hormonal cascades, gut repair mechanisms, and epigenetic changes beyond typical intermittent fasting.
A 6-month fasting-mimicking diet restored fat-burning flexibility and improved albuminuria in T2D patients, with metabolomics revealing who responds best.
New rat study reveals alternate day fasting protocols outperform time-restricted eating for weight loss and HDL cholesterol.