Methylene Blue Emerges as a Versatile Clinical Tool Beyond Emergency Medicine
A comprehensive review reveals methylene blue's expanding role from toxicology emergencies to perioperative care, neurology, and oncology.
20 articles
A comprehensive review reveals methylene blue's expanding role from toxicology emergencies to perioperative care, neurology, and oncology.
Current labeling urges nursing mothers to pause breastfeeding for 8 days after methylene blue, but the underlying evidence is thin.
FDA-approved methylene blue reduced delirium-like behavior in surgical mice by suppressing neuroinflammation and repairing the blood-brain barrier.
A meta-analysis of 15 studies finds methylene blue therapy significantly reduces mortality in ICU septic shock patients, with hemodynamic benefits.
A 2025 review examines how methylene blue's nitric oxide inhibition can restore vascular tone in septic and vasoplegic shock patients.
A primate study shows methylene blue treats fatal cerebral malaria and uncovers neutrophil-linked genes as diagnostic biomarkers.
Un ECR multicentrique portant sur 566 patients, lancé à travers la Chine, visant à déterminer si l'administration précoce de bleu de méthylène réduit la mortalité à 28 jours dans le choc septique dépendant de vasopresseurs à haute dose.
Une étude portant sur 200 patients constate qu'un recours précoce au methylene blue dans le choc vasoplégique post-pontage réduit de moitié la durée de séjour en soins intensifs et diminue les taux d'insuffisance rénale.
Un rapport de cas du Surrey and Sussex NHS Trust met en évidence les risques d'extravasation du bleu de méthylène dans la main et l'avant-bras lors d'une chirurgie parathyroïdienne.
A comprehensive review reveals how advanced oxidation processes can efficiently degrade methylene blue, a persistent textile pollutant threatening human health.
Adding methylene blue to ropivacaine in a serratus anterior plane block significantly prolongs pain relief up to 72 hours post-op.
A comprehensive review reveals how plant-derived nanomaterials catalytically neutralize toxic dyes and nitrophenols from industrial wastewater with remarkable efficiency.
New research shows blue light triggers harmful changes in retinal cells by disrupting mitochondrial function, offering targets for AMD prevention.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
A 4-week-old infant developed severe methemoglobinemia after EMLA cream was applied for circumcision, highlighting hidden dangers of topical anesthetics.
Une méta-analyse Cochrane portant sur 17 essais contrôlés randomisés montre que la RTUV en lumière bleue réduit la récidive et la progression du cancer de la vessie, notamment chez les patients à risque intermédiaire et élevé.
Morning blue light exposure stabilized attention during cognitive tasks, reducing moment-to-moment mental variability in young adults.
A 303-tumor study shows DNA methylation arrays can classify neuroblastoma into prognostically meaningful subgroups, potentially replacing multiple genomic tests.
La cyanidin-3-O-glucoside, une anthocyanine naturelle, réduit les lymphocytes T régulateurs (Tregs) immunosuppresseurs et ralentit la progression du myélome multiple chez la souris et dans des études cellulaires.
Delphinidin, a natural anthocyanin, prevented microglial senescence via AMPK/SIRT1 signaling, reducing amyloid plaques and restoring cognition in AD mice.