PROMETHEUS Trial Tests Personalized Supplements and Lifestyle for Healthy Aging
An 8-week feasibility trial combines NMN, urolithin A, creatine, and exercise to target individual aging patterns.
Evidence-based supplements, vitamins, minerals, nootropics, and longevity interventions
227 articles
An 8-week feasibility trial combines NMN, urolithin A, creatine, and exercise to target individual aging patterns.
A comprehensive 2025 review synthesizes clinical and preclinical evidence that ashwagandha counters core aging mechanisms from telomere attrition to inflammaging.
A 12-week RCT shows a targeted supplement combo significantly lowers inflammatory biomarkers in healthy older adults, especially those eating pro-inflammatory diets.
NAD+ decline drives mitochondrial dysfunction in retinitis pigmentosa. Oral NMN reversed retinal damage in rats via a newly identified metabolic pathway.
A C. elegans study finds V14™ outperforms AG1® in preserving movement with age, with transcriptomics revealing metabolic and stress-response pathway shifts.
A completed University of São Paulo trial explored whether taurine supplementation can reduce oxidative stress — a key driver of aging.
A Bayesian network meta-analysis of 12 trials finds CAF+TAU co-supplementation outperforms each compound alone for anaerobic capacity and reaction time.
A Phase 1/2 trial evaluates whether an mRNA-based quadrivalent influenza vaccine can match or beat standard and high-dose comparators in adults.
Independent testing reveals rampant quality failures in NMN, NR, and NAD+ supplements. Know what to look for before buying.
Independent testing exposes widespread quality failures in NAD+ precursor supplements, with actionable guidance on which brands actually deliver.
Riboflavin (vitamin B2) inhibits Cryptococcus neoformans growth, dismantles biofilms, and reduces organ fungal burden in mouse models of meningitis and pneumonia.
Expert reviews confirm NR and NMN raise blood NAD+, but longevity proof remains elusive and product quality varies widely.