Human Milk Oligosaccharides Shape Infant Gut Microbiome Well Past Breastfeeding
A large cohort study finds HMOs have age-dependent, structure-specific effects on infant gut bacteria that persist to 13 months.
20 articles
A large cohort study finds HMOs have age-dependent, structure-specific effects on infant gut bacteria that persist to 13 months.
Human milk oligosaccharides shape beneficial gut bacteria in infants, providing lifelong protection against infections and chronic diseases.
Une revue de référence révèle comment les composés bioactifs du lait maternel programment le microbiote intestinal du nourrisson, son immunité et son risque de maladies à long terme.
A 6-week RCT shows 2′-fucosyllactose raises Bifidobacterium, HDL, insulin, and FGF21 in adults over 60, with cognitive benefits in responders.
New lipidomics research reveals breast milk positions DHA and palmitic acid differently than maternal or fetal blood, suggesting a purposeful metabolic design.
Study shows 2'-fucosyllactose improves cognitive function in mice by modulating gut microbiota and brain serotonin levels.
New research reveals oxytocin signals fat cells to release lipids for milk, reshaping our understanding of lactation biology.
CGM data reveals infants fed corn syrup solid-based formulas show significantly greater glycemic variability than those fed breast milk or lactose-based formula.
Des réseaux de microréseaux de glycanes synthétiques révèlent comment les systèmes immunitaires humain et murin répondent à *Candida*, en identifiant des cibles oligosaccharidiques clés pour le diagnostic et les vaccins.
L'oligosaccharide H3N2b atteint une précision diagnostique de 100 % dans le plasma et le LCR, et diminue après une thérapie génique par AAV9 — une avancée majeure pour cette maladie cérébrale fatale.
A fetal enzyme floods newborns with hyocholic acids that train immune tolerance and shape a healthy gut microbiome—then disappear by adulthood.
SLC35A2-CDG disrupts ganglioside synthesis, not just protein glycosylation. Galactose supplementation restores lipid glycosylation and may explain neurological benefits.
Moins de 2 % de l'acarbose est absorbé par la mère, ce qui rend l'exposition du nourrisson via le lait maternel extrêmement improbable.
New research reveals that solid food source affects gut bacteria differently depending on whether babies are breastfed or formula-fed.
Comprehensive review reveals how infant gut bacteria development in first 1000 days determines chronic disease risk throughout life.
New research reveals which plant milk delivers superior cholesterol reduction and disease-fighting compounds for optimal health.
120-person trial tested whether Oligonol could reduce muscle loss and cardiovascular risks in middle-aged and older adults.
Study reveals how beneficial bacteria travel from gut to ovaries, improving reproductive function and delaying aging in laying hens.
New research reveals distinct patterns of intestinal microbiome development in mice, with implications for understanding human infant gut health.
Le profilage des N-glycanes plasmatiques permet de distinguer la SEP de la NMOSD à anticorps anti-AQP4 et du MOGAD avec une précision allant jusqu'à 80,5 %, offrant ainsi un complément diagnostique non invasif.