Human Milk Oligosaccharides Shape Infant Gut Microbiome Well Past Breastfeeding
A large cohort study finds HMOs have age-dependent, structure-specific effects on infant gut bacteria that persist to 13 months.
20 articles
A large cohort study finds HMOs have age-dependent, structure-specific effects on infant gut bacteria that persist to 13 months.
Human milk oligosaccharides shape beneficial gut bacteria in infants, providing lifelong protection against infections and chronic diseases.
A landmark review reveals how human milk's bioactive compounds program infant gut microbiota, immunity, and long-term disease risk.
A 6-week RCT shows 2β²-fucosyllactose raises Bifidobacterium, HDL, insulin, and FGF21 in adults over 60, with cognitive benefits in responders.
New lipidomics research reveals breast milk positions DHA and palmitic acid differently than maternal or fetal blood, suggesting a purposeful metabolic design.
Study shows 2'-fucosyllactose improves cognitive function in mice by modulating gut microbiota and brain serotonin levels.
New research reveals oxytocin signals fat cells to release lipids for milk, reshaping our understanding of lactation biology.
CGM data reveals infants fed corn syrup solid-based formulas show significantly greater glycemic variability than those fed breast milk or lactose-based formula.
Synthetic glycan microarrays reveal how human and mouse immune systems respond to Candida, pinpointing key oligosaccharide targets for diagnostics and vaccines.
The oligosaccharide H3N2b achieves 100% diagnostic accuracy in plasma and CSF and falls with AAV9 gene therapy β a breakthrough for this fatal brain disease.
A fetal enzyme floods newborns with hyocholic acids that train immune tolerance and shape a healthy gut microbiomeβthen disappear by adulthood.
SLC35A2-CDG disrupts ganglioside synthesis, not just protein glycosylation. Galactose supplementation restores lipid glycosylation and may explain neurological benefits.
Less than 2% of acarbose is absorbed by the mother, making infant exposure via breastmilk extremely unlikely.
New research reveals that solid food source affects gut bacteria differently depending on whether babies are breastfed or formula-fed.
Comprehensive review reveals how infant gut bacteria development in first 1000 days determines chronic disease risk throughout life.
New research reveals which plant milk delivers superior cholesterol reduction and disease-fighting compounds for optimal health.
120-person trial tested whether Oligonol could reduce muscle loss and cardiovascular risks in middle-aged and older adults.
Study reveals how beneficial bacteria travel from gut to ovaries, improving reproductive function and delaying aging in laying hens.
New research reveals distinct patterns of intestinal microbiome development in mice, with implications for understanding human infant gut health.
Plasma N-glycan profiling distinguishes MS from AQP4-Ab NMOSD and MOGAD with up to 80.5% accuracy, offering a noninvasive diagnostic complement.