290 articles in this topic
A sweeping 2025 review reveals ghrelin's roles span immunity, neuroprotection, cardiovascular health, and addiction beyond appetite.
Deleting GHSR in macrophages cuts liver fibrosis markers and inflammation in mice, revealing a druggable signaling axis.
Adenosine 5'-monophosphate preserves muscle mass during sepsis by activating AMPK and blocking IL-1β, offering a potential new therapy.
Imaging 16 million pancreatic cells reveals macrophage-T cell interactions and beta-cell stress signatures at the earliest, preclinical stages of type 1 diabetes.
A new PTM called lysine pyruvylation links glycolytic activity directly to gene regulation, with SIRT3 acting as the eraser.
A 745-person genomic study identifies why metformin concentrations vary so widely — with ancestry-specific genetic variants playing a key role.
A randomized trial shows that extending overnight fasting by 3 hours, timed to sleep, cuts nighttime heart rate and improves glucose control.
New analysis finds delayed stomach emptying accounts for only 4–6% of appetite suppression from liraglutide, challenging a popular assumption.
A 16-week RCT finds metformin blocks exercise-induced improvements in artery and capillary function in adults at metabolic syndrome risk.
AICAR-driven AMPK activation rescues mitochondrial energy balance in hypoxic corneal cells, pointing to a new therapy for keratopathy.
New sensor data shows type 1 diabetics on ketogenic diets experience frequent, short-lived, asymptomatic ketosis episodes — mostly harmless.
People with schizophrenia exposed to the most nighttime light face 4x higher obesity odds and 3x higher hypertension odds.
