Mitochondria-Nucleus Communication Breakdown May Drive Alzheimer's Before Plaques Form
A new review reveals that disrupted mito-nuclear signaling may precede amyloid and tau pathology, opening fresh therapeutic targets for Alzheimer's.
446 articles in this topic
A new review reveals that disrupted mito-nuclear signaling may precede amyloid and tau pathology, opening fresh therapeutic targets for Alzheimer's.
AI framework Reti-Pioneer screens for seven systemic diseases from a retinal photo, outperforming standard lab tests in speed and accuracy.
How you spend your 24 hours โ sleeping, sitting, or moving โ determines your baseline brain function and exercise responsiveness.
A Framingham study of 2,844 adults links impaired endothelial function to higher Alzheimer's risk, brain shrinkage, and white matter damage.
A new AI classifier using just 15 proteins achieves 95.5% AUC accuracy across Alzheimer's, Parkinson's, FTD, and Lewy body dementia.
New research reveals how the brain decides which memories to link โ and which to keep separate โ with major implications for cognition and dementia.
A six-camera 3D system tracks whole-face mouse movements at sub-mm precision, unlocking new windows into neural and physiological states.
New research reveals brain movement inside the skull is mechanically driven by abdominal contractions, not heartbeat or breathing.
New single-nucleus RNA sequencing reveals immature neurons persist in aged human hippocampus and may actively support cognitive resilience in Alzheimer's disease.
Groundbreaking research shows neural anticipation of a virtual infection activates measurable immune responses, revealing a direct brain-immune axis.
A ยต-opioid receptor superagonist shows strong analgesic potency in preclinical work while minimizing addiction, respiratory depression, and other classic opioid harms.
Overexpressing Sox9 in brain support cells triggers plaque cleanup and protects cognition in Alzheimer's mouse models.