562 articles in this topic
A landmark multicohort proteomics study reveals how APOE2 and APOE4 shape Alzheimer's risk through entirely distinct molecular mechanisms.
New research shows single V1 neurons in the visual cortex track internal arousal states, directly predicting perception and reaction speed.
New research reveals how the brain selectively triggers learning only during meaningful errors — not random neural noise.
A landmark Nature Neuroscience study reveals how peripheral immune cells infiltrate the spinal cord in ALS, pointing to targeted immunotherapy.
A master autophagy regulator drops with age and in AD patients — restoring it in mice clears amyloid, reduces tau, and rescues cognition.
LINE-1 retrotransposons act as alternative gene promoters in human stem cells, and silencing them shrinks cerebral organoids.
Scientists used stem cell-derived vesicles to deliver light-activated gene therapy to the brain without surgery, reversing cognitive decline in Alzheimer's mice.
A bibliometric analysis of 595 papers maps how glymphatic-Alzheimer's research has grown exponentially, pinpointing AQP4, sleep, and DTI-ALPS imaging as the hottest frontiers.
Cerebral hypoperfusion drives glymphatic dysfunction in systemic inflammation — and restoring blood flow with levosimendan reverses it.
HIE disrupts the glymphatic system in neonatal brains, impairing waste clearance and development with lasting consequences.
A comprehensive review details how NMOSD, MOGAD, and other rare CNS disorders are frequently mistaken for MS — and how to tell them apart.
Boosting BNIP3 in muscle tissue extends fly lifespan and shields the brain from age-related degeneration via a muscle-brain signaling axis.
