Massive Brain Atlas Maps How Neurotransmitter Systems Break Down With Age and Disease
A multi-omics analysis of over 1 million brain cells reveals how neurotransmitter systems change across aging and eight neuropsychiatric disorders.
562 articles in this topic
A multi-omics analysis of over 1 million brain cells reveals how neurotransmitter systems change across aging and eight neuropsychiatric disorders.
A major review reveals how the glymphatic system's failure drives neurodegeneration and brain tumor resistance — and how to fix it.
Blocking brain lymphatic drainage triggers age-dependent compensatory responses — young rats adapt, middle-aged rats largely cannot, with proteomic signs of neurodegeneration in both.
New mouse study reveals how the brain's waste-clearance system modulates toxic protein buildup linked to Parkinson's disease.
PET-MRI study of 54 cSVD patients links microglial activation to enlarged white matter perivascular spaces, not BBB leakage.
Inhibiting TRPV4 channels in mice restored glymphatic drainage, cut cerebral edema, and improved neurological recovery after ischemic stroke.
A new study warns that diabetes medications could confound Alzheimer's biomarker studies, distorting our understanding of the diabetes-dementia link.
A formal erratum updates a 2026 cross-sectional survey on mental health factors affecting early-career dementia researchers worldwide.
A key potassium channel, KCNA4, is lost in vulnerable brainstem neurons at Braak II — potentially fueling tau pathology progression.
A real-time brain-computer interface decodes auditory attention and amplifies the speaker you choose, beating today's hearing aids.
New research pinpoints the hippocampal dorsal CA1 as the neural hub encoding individual differences in prosocial vs. selfish behavior.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.