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Simufilam Alzheimer's Trial Terminated Before Completing Phase 3
Brain Health

Simufilam Alzheimer's Trial Terminated Before Completing Phase 3

Cassava Sciences' 76-week Phase 3 trial of simufilam for Alzheimer's was terminated, raising questions about the drug's future.

Clinical Trial
Jun 1, 2026 0
PRF and CGF Scaffolds Tested Against Blood Clot for Regrowing Dead Tooth Roots
Regenerative Medicine

PRF and CGF Scaffolds Tested Against Blood Clot for Regrowing Dead Tooth Roots

A 12-month RCT compares three scaffold types and two EDTA concentrations for regenerating necrotic immature permanent teeth.

Clinical Trial
May 31, 2026 0
Columbia Study Tests Group-Based Family Nurture Intervention for Preschoolers
Brain Health

Columbia Study Tests Group-Based Family Nurture Intervention for Preschoolers

A completed Columbia University trial compares Family Nurture Intervention in group settings to standard programs for children ages 2–4.5.

Clinical Trial
May 31, 2026 0
Combining NR Supplements With Exercise May Finally Unlock NAD+ Benefits in Humans
Exercise & Fitness

Combining NR Supplements With Exercise May Finally Unlock NAD+ Benefits in Humans

A completed Maastricht University trial tests whether pairing NR supplementation with exercise can boost NAD+ levels and reverse metabolic dysfunction in overweight adults.

Clinical Trial
May 30, 2026 0
CanSino's Adenovirus COVID-19 Vaccine Shows Safety and Immune Response in Phase I Trial
Autoimmune & Arthritis

CanSino's Adenovirus COVID-19 Vaccine Shows Safety and Immune Response in Phase I Trial

A landmark Phase I trial of 108 adults tested the first adenovirus-vectored COVID-19 vaccine for safety and immune response.

Clinical Trial
May 30, 2026 0
L-Arginine Tested to Restore Erectile Function in Prostate Cancer Radiation Survivors
Cancer Research

L-Arginine Tested to Restore Erectile Function in Prostate Cancer Radiation Survivors

A phase II trial explores whether the amino acid L-arginine, with or without enzyme inhibitors, can improve erectile function and quality of life after prostate cancer radiation therapy.

Clinical Trial
May 29, 2026 0
Pfizer-BioNTech Pivotal Trial Confirms BNT162b2 Safety and Efficacy Across Ages
Longevity & Aging

Pfizer-BioNTech Pivotal Trial Confirms BNT162b2 Safety and Efficacy Across Ages

The landmark Phase 1/2/3 trial that brought mRNA COVID-19 vaccination to the world, now completed with booster and variant data.

Clinical Trial
May 29, 2026 0
T-VEC Plus Pembrolizumab Tested in Melanoma After Anti-PD-1 Failure
Cancer Research

T-VEC Plus Pembrolizumab Tested in Melanoma After Anti-PD-1 Failure

Phase 2 trial explores whether combining oncolytic virus therapy with immunotherapy can rescue patients whose melanoma progressed on PD-1 blockade.

Clinical Trial
May 29, 2026 0
Whole-Cell Breast Cancer Vaccine Plus PD-1 Inhibitor Targets Treatment-Resistant Metastatic Disease
Cancer Research

Whole-Cell Breast Cancer Vaccine Plus PD-1 Inhibitor Targets Treatment-Resistant Metastatic Disease

A phase I/II trial tests SV-BR-1-GM, a whole-cell cancer vaccine, combined with the checkpoint inhibitor retifanlimab in patients with metastatic breast cancer.

Clinical Trial
May 29, 2026 0
Duke Study Tests Blood Biomarker to Catch Alzheimer's Before Symptoms Strike
Brain Health

Duke Study Tests Blood Biomarker to Catch Alzheimer's Before Symptoms Strike

Researchers at Duke University tested a blood-based biomarker to stratify Alzheimer's patients from healthy adults, aiming to enable earlier detection.

Clinical Trial
May 29, 2026 0
REGENXBIO Hunts LDLR Mutations to Build a Gene Therapy Pipeline for Rare Cholesterol Disorder
Heart Health

REGENXBIO Hunts LDLR Mutations to Build a Gene Therapy Pipeline for Rare Cholesterol Disorder

A completed registry study identified and genotyped HoFH patients with LDLR mutations, laying groundwork for targeted gene therapy.

Clinical Trial
May 28, 2026 0
Dasatinib and Quercetin Reach the Brain in Early Alzheimer's Patients
Brain Health

Dasatinib and Quercetin Reach the Brain in Early Alzheimer's Patients

A completed Phase 1/2 pilot trial tested whether the senolytic duo D+Q penetrates the brain in early Alzheimer's disease.

Clinical Trial
May 28, 2026 0
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