Inherited Bone Marrow Failure Syndromes Explained from Root Causes to Clinical Signs
A comprehensive review of inherited bone marrow failure, covering genetic causes, major syndromes, and the cytopenias that define them.
6,382 articles
A comprehensive review of inherited bone marrow failure, covering genetic causes, major syndromes, and the cytopenias that define them.
A 16-week RCT finds metformin blocks exercise-induced improvements in artery and capillary function in adults at metabolic syndrome risk.
A comprehensive 2026 review maps every major ergogenic and medical supplement to cycling physiology, with evidence grades for each.
High-intensity home cycling improved ataxia symptoms, fatigue, and VO2max significantly more than dose-matched balance training over one year.
A Nature study reveals peripheral immune cells migrate to the brain during sleep to clear toxic lipids — and disrupting this causes memory loss and shortened lifespan.
A mouse study shows CD38 inhibition protects colon architecture during 5-FU chemotherapy by preventing NAD+ depletion.
AICAR-driven AMPK activation rescues mitochondrial energy balance in hypoxic corneal cells, pointing to a new therapy for keratopathy.
New sensor data shows type 1 diabetics on ketogenic diets experience frequent, short-lived, asymptomatic ketosis episodes — mostly harmless.
A new meta-analysis finds women with premature adrenarche carry lasting metabolic and reproductive risks into adulthood.
A 20-year study of 1,801 American Indians links specific plasma lipid species to diastolic heart aging and coronary heart disease risk.
An AI-engineered antisense oligonucleotide slashes toxic progerin levels, reverses cardiovascular damage, and dramatically extends lifespan in progeria models.
A large-scale genomic study identifies 39 shared genetic loci between schizophrenia and Alzheimer's disease, converging on chromosome 16p11.2.