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Inherited Bone Marrow Failure Syndromes Explained from Root Causes to Clinical Signs
Regenerative Medicine

Inherited Bone Marrow Failure Syndromes Explained from Root Causes to Clinical Signs

A comprehensive review of inherited bone marrow failure, covering genetic causes, major syndromes, and the cytopenias that define them.

Research Paper
Jul 2, 2026 0
Metformin Undermines Exercise Gains in Vascular Insulin Sensitivity
Metabolic Health

Metformin Undermines Exercise Gains in Vascular Insulin Sensitivity

A 16-week RCT finds metformin blocks exercise-induced improvements in artery and capillary function in adults at metabolic syndrome risk.

Research Paper
Jul 2, 2026 0
The Complete Cyclist's Guide to Supplements Backed by Science
Exercise & Fitness

The Complete Cyclist's Guide to Supplements Backed by Science

A comprehensive 2026 review maps every major ergogenic and medical supplement to cycling physiology, with evidence grades for each.

Research Paper
Jul 2, 2026 0
Home Aerobic Exercise Beats Balance Training for Cerebellar Ataxia in 12-Month RCT
Brain Health

Home Aerobic Exercise Beats Balance Training for Cerebellar Ataxia in 12-Month RCT

High-intensity home cycling improved ataxia symptoms, fatigue, and VO2max significantly more than dose-matched balance training over one year.

Research Paper
Jul 2, 2026 0
Your Blood Cells Clean the Brain During Sleep — And Without Them, Memory Fails
Sleep & Recovery

Your Blood Cells Clean the Brain During Sleep — And Without Them, Memory Fails

A Nature study reveals peripheral immune cells migrate to the brain during sleep to clear toxic lipids — and disrupting this causes memory loss and shortened lifespan.

Research Paper
Jul 2, 2026 0
Blocking CD38 Preserves Gut Lining During Chemotherapy by Restoring NAD+
Gut & Microbiome

Blocking CD38 Preserves Gut Lining During Chemotherapy by Restoring NAD+

A mouse study shows CD38 inhibition protects colon architecture during 5-FU chemotherapy by preventing NAD+ depletion.

Research Paper
Jul 2, 2026 0
AMPK Activation Restores Mitochondrial Function in Oxygen-Starved Corneal Cells
Metabolic Health

AMPK Activation Restores Mitochondrial Function in Oxygen-Starved Corneal Cells

AICAR-driven AMPK activation rescues mitochondrial energy balance in hypoxic corneal cells, pointing to a new therapy for keratopathy.

Research Paper
Jul 2, 2026 0
Continuous Ketone Sensors Reveal Frequent Benign Ketosis in Type 1 Diabetes on Low-Carb Diets
Metabolic Health

Continuous Ketone Sensors Reveal Frequent Benign Ketosis in Type 1 Diabetes on Low-Carb Diets

New sensor data shows type 1 diabetics on ketogenic diets experience frequent, short-lived, asymptomatic ketosis episodes — mostly harmless.

Research Paper
Jul 2, 2026 0
Girls With Early Adrenarche Face Higher Insulin Resistance and Hormonal Risks as Adults
Hormones

Girls With Early Adrenarche Face Higher Insulin Resistance and Hormonal Risks as Adults

A new meta-analysis finds women with premature adrenarche carry lasting metabolic and reproductive risks into adulthood.

Research Paper
Jul 2, 2026 0
Blood Lipid Signatures in Midlife Predict Heart Aging and Future Heart Disease Risk
Heart Health

Blood Lipid Signatures in Midlife Predict Heart Aging and Future Heart Disease Risk

A 20-year study of 1,801 American Indians links specific plasma lipid species to diastolic heart aging and coronary heart disease risk.

Research Paper
Jul 2, 2026 0
AI-Designed Gene Therapy Extends Lifespan 83% in Progeria Mouse Models
Longevity & Aging

AI-Designed Gene Therapy Extends Lifespan 83% in Progeria Mouse Models

An AI-engineered antisense oligonucleotide slashes toxic progerin levels, reverses cardiovascular damage, and dramatically extends lifespan in progeria models.

Research Paper
Jul 2, 2026 0
Schizophrenia and Dementia Share Genetic Roots at Brain Vulnerability Hotspot
Brain Health

Schizophrenia and Dementia Share Genetic Roots at Brain Vulnerability Hotspot

A large-scale genomic study identifies 39 shared genetic loci between schizophrenia and Alzheimer's disease, converging on chromosome 16p11.2.

Research Paper
Jul 2, 2026 0
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