Longevity & Aging
Rare Kidney Disease Leaves Distinct Sugar Fingerprints in Blood
Nephropathic Cystinosis alters serum N-glycosylation patterns, especially sialylation, offering potential new disease biomarkers.
Research Paper
May 17, 2026 0
All Articles
5061 articles
Longevity & Aging
IV Iron Therapy Fails to Cut Heart Failure Deaths in Landmark FAIR-HF2 Trial
The FAIR-HF2 trial tested intravenous ferric carboxymaltose in iron-deficient heart failure patients, with surprising results for hard clinical endpoints.
Research Paper
May 17, 2026 0
Longevity & Aging
AMPK Pathway Emerges as Master Switch for Mitochondrial Rejuvenation
A comprehensive 2025 review reveals how AMPK orchestrates mitochondrial fission, mitophagy, and biogenesis to restore cellular energy homeostasis.
Research Paper
May 17, 2026 0
Longevity & Aging
Diabetes Drugs Activate Key Brain Pathway to Fight Alzheimer's Disease
GLP-1 receptor agonists like semaglutide activate AMPK signaling to reduce amyloid plaques and restore memory in Alzheimer's mouse models.
Research Paper
May 17, 2026 0
Longevity & Aging
Lysosomes Rewrite the Epigenome to Pass Longevity Signals Across Generations
A lysosome-to-epigenome pathway in C. elegans extends lifespan across multiple generations via histone H3.3 transport from gut to germline.
Research Paper
May 17, 2026 0
Longevity & Aging
Meal Timing Supercharges Exercise Through Fat-Muscle Metabolic Crosstalk
New research reveals how when you eat reshapes adipocyte signaling to boost endurance — and identifies a druggable target to mimic the effect.
Research Paper
May 17, 2026 0
Longevity & Aging
Wnt and mTOR Signaling Team Up to Control Primary Cilia Formation in Human Cells
A new study reveals that too much or too little Wnt signaling disrupts cilia formation, with mTOR inhibition rescuing the defect.
Research Paper
May 17, 2026 0
Longevity & Aging
Telomerase Structural Biology Reveals How Cells Maintain Chromosome Ends
A 2026 review maps the molecular architecture of telomerase across four model organisms, illuminating cancer and aging disease mechanisms.
Research Paper
May 17, 2026 0
Longevity & Aging
Endurance Athletes Show 2x Higher Telomerase Gene Expression Than Sedentary Peers
Middle-aged marathon runners showed 2.06-fold higher hTERT expression and significant cardiac adaptations compared to inactive controls.
Research Paper
May 17, 2026 0
Longevity & Aging
Bowhead Whales Carry Superior DNA Repair Machinery Linked to Their 200-Year Lifespan
Scientists find bowhead whale cells repair DNA damage faster and more accurately than other mammals, offering clues to extreme longevity.
Research Paper
May 17, 2026 0
Longevity & Aging
Iron Overload Drives Premature Ovarian Aging in Endometriosis-Linked Infertility
Single-cell and spatial transcriptomics reveal how excess iron triggers cellular senescence and metabolic dysfunction in ovarian follicles, explaining poor oocyte quality in endometriosis.
Research Paper
May 17, 2026 0
Longevity & Aging
Human Immune Atlas Maps How Immunity Rewires Itself Before Old Age
A landmark multi-omic study of 300+ adults reveals non-linear T cell reprogramming and TH2 bias in midlife that blunts vaccine responses.
Research Paper
May 17, 2026 0