562 articles in this topic
A Harvard-developed digital seed amplification assay can precisely quantify TDP-43 protein aggregates in CSF, offering a potential diagnostic breakthrough for frontotemporal dementia.
JAMA publishes a poem exploring the intersection of medicine and verse, reflecting on the human dimensions of clinical practice.
A short literary piece in JAMA offers a humanizing perspective on clinical care and the patient-physician relationship.
Scientists image NMDA receptors at atomic resolution, uncovering how calcium enters and magnesium blocks the channel underlying neuroplasticity.
New research links excess astrocytic cholesterol to impaired brain clearance — a potential key mechanism driving Alzheimer's progression.
fMRI study finds sport participation — not collision exposure — shapes neural processing in children's inhibitory control.
A memory clinic study finds 70% of patients tested positive for Alzheimer's pathology, with testing volumes exploding since new treatments arrived.
Combining polygenic and transcriptional risk scores from blood raises Alzheimer's detection accuracy, offering a less invasive screening path.
New research reveals dendrite branching is driven by random growth, with ligand contacts acting as brakes to sculpt precise neural architecture.
New research reveals microglia actively silence and reshape fear-encoding neurons during extinction learning, opening new PTSD treatment avenues.
A new NEJM case report highlights cerebral amyloid angiopathy, a vascular brain condition closely tied to cognitive decline and stroke risk.
Cognitive reserve helps language performance early in svPPA, but accelerates decline once brain volume drops significantly.
