Blood-Based Nanoparticles Detect Alzheimer's Risk Before Symptoms Appear
A 4-protein panel in neuronal extracellular vesicles outperforms standard plasma tests in flagging early Alzheimer's brain changes.
562 articles in this topic
A 4-protein panel in neuronal extracellular vesicles outperforms standard plasma tests in flagging early Alzheimer's brain changes.
New research maps a stress-signaling cascade linking p53 activation to brain inflammation and depression, with curcumin interrupting it.
A comprehensive review examines how marine-derived bioactives like omega-3s, astaxanthin, and polysaccharides may combat chronic neuroinflammation underlying major neurodegenerative diseases.
New research reveals how glucose availability directs brain cell proliferation via a metabolic-epigenetic axis, with implications for MS and brain repair.
A meta-analysis of 684,493 patients finds just 49% persist with anti-dementia drugs at 12 months, with major variation by drug type and study methodology.
A multi-cohort study finds that every 5 km closer to a lead-releasing facility is tied to measurably lower episodic memory scores.
Intracranial recordings reveal a low-dimensional subspace in human prefrontal cortex that selectively transmits context-relevant signals to motor cortex.
Norwegian cohort study finds paternal valproate users have significantly higher epilepsy polygenic risk scores, suggesting genetic confounding may explain reported child neurodevelopmental risks.
A year-long sham-controlled trial finds active VNS meaningfully improves daily function and quality of life in patients who failed 4+ antidepressants.
A 2018 paper on antileukotriene therapy and tau phosphorylation in Alzheimer's mice has been retracted due to image fraud.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
Neuropixels recordings reveal how laminar microcircuits generate interictal epileptiform discharges — and how to predict them 1 second in advance.