562 articles in this topic
New research links multimorbidity — especially cardiometabolic disease clusters — to measurable brain-age acceleration in dementia-free older adults.
New research reveals how lipid droplets spark the protein aggregation at the heart of Parkinson's disease, disrupting energy metabolism.
Older adults with higher cardiorespiratory fitness had ~48% lower Alzheimer's risk over 8.7 years, with a clear VO2 threshold identified.
Two small clinical trials show BCG vaccination alters immune activity in cerebrospinal fluid and changes amyloid-β levels in older adults.
High-intensity home cycling improved ataxia symptoms, fatigue, and VO2max significantly more than dose-matched balance training over one year.
A large-scale genomic study identifies 39 shared genetic loci between schizophrenia and Alzheimer's disease, converging on chromosome 16p11.2.
A nested study within the PREDIMED trial finds elevated resistin — an adipose-derived hormone — associated with 56% higher odds of incident Alzheimer's disease.
First large proteomic study in Nigerian and Tanzanian adults links plasma proteins to amyloid pathology, expanding Alzheimer's biomarker research beyond Western cohorts.
New research proposes delirium as the key mechanistic link explaining why severe infections dramatically raise dementia risk.
New research reveals normal Tau protein limits mitochondrial efficiency — its absence boosts energy output and stress resistance.
New research identifies plasma and CSF tau biomarkers that closely mirror tau PET scans, potentially replacing costly brain imaging.
A large study of 2,795 adults finds OSA is associated with worse memory and elevated dementia risk scores, partly explained by vascular risk factors.
