484 articles in this topic
Scientists expand granulocyte-monocyte progenitors into a scalable CAR platform that infiltrates tumors and fights leukemia and solid cancers.
MD Anderson researchers reveal a feedback loop between cuproptosis and CD8+ T cells that could unlock new combination therapies for immune-resistant tumors.
A novel liquid biopsy scoring tool called MinerVa-Delta predicted survival in advanced lung cancer with striking accuracy, even when imaging was ambiguous.
Fate-AI integrates DNA fragmentation and methylation signals to detect 10 cancer types from blood with AUCs up to 0.97.
Targeting a single protein in immune cells rewires cholesterol metabolism to flip immunosuppressive macrophages into tumor-fighting ones.
New review from Nature Cancer reveals how immune-organizing structures inside tumors could predict and enhance immunotherapy response.
Scientists found that inhibiting USP30, a mitochondrial enzyme, restores immune cell function and shrinks tumors in mice.
Scientists identify a mitochondria-proteasome-haem pathway that silences immune cells — and show bortezomib can fix it in CAR-T therapy.
A new Science paper reveals that mitochondrial fitness in dendritic cells controls antitumor immunity — and can be targeted to boost immunotherapy.
A new review reveals how cholangiocarcinoma hijacks the nervous system to invade tissue and suppress immune defenses.
Cell Metabolism has published an erratum (correction notice) for a 2022 paper reporting that cancer cells co-opt nociceptive nerves to survive nutrient stress.
Genomic study reveals 20% of post-CD38-therapy myeloma patients show CD38 loss, including biallelic escape conferring permanent drug resistance.
