381 articles in this topic
Researchers identify four LSC subtypes that predict venetoclax resistance and reveal matched subtype-specific therapies for AML patients.
A new editorial in Gut explores how AI-powered radiomic analysis could identify occult pancreatic cancer missed by standard imaging.
The landmark NordICC trial's 13-year data shows one colonoscopy meaningfully reduces cancer incidence but doesn't significantly lower mortality.
Researchers discover a BBB-like vascular shield in small cell lung cancer that blocks immune cells — and find a drug combo to overcome it.
Long-elusive cancer-driving proteins are yielding to innovative drug strategies, opening new frontiers in oncology treatment.
A Nature study reveals neurons physically transfer mitochondria to breast cancer cells via tunneling nanotubes, boosting metastatic potential.
A high-MAPK, low-WNT tumor cell state drives CRC metastasis, and blocking mutant KRAS suppresses it in mice.
A mouse study finds that senolytic drugs cannot prevent chemotherapy-driven bone loss, challenging a leading hypothesis about its cause.
A comprehensive review reveals how iron-driven cell death can be exploited to treat ATC, one of the most lethal human cancers.
A cancer patient on nivolumab developed Eikenella corrodens bacteremia after CNS infection, revealing how immune checkpoint therapy may enable dangerous microbial dissemination.
Tissue stiffness triggers a chain reaction — recruiting macrophages that generate DNA-damaging lipid byproducts — linking fibrosis directly to cancer initiation.
Tumor cells in intrahepatic cholangiocarcinoma hijack IL-6 signaling to fuel growth — creating a targetable metabolic vulnerability.
