Multiple Sclerosis May Begin With Vascular and Metabolic Changes
A new minireview reveals early vascular aging, endothelial dysfunction, and insulin resistance may drive MS pathogenesis before disability sets in.
140 articles
A new minireview reveals early vascular aging, endothelial dysfunction, and insulin resistance may drive MS pathogenesis before disability sets in.
A new review maps how blood stem cell metabolism shifts with aging and how leukemia hijacks those changes — pointing to targeted therapeutic strategies.
A new review traces how aging science evolved from single-cause theories to partial reprogramming with Yamanaka factors as a lifespan-extending strategy.
A new Nature Metabolism review reveals how mitochondrial maintenance systems govern healthy aging — and how NAD+, AMPK, and caloric restriction may restore them.
A meta-analysis of 8 studies finds intermittent fasting significantly reduces liver fat and improves key metabolic markers in MASLD patients.
A landmark Nature Immunology review reveals adaptive immune cells actively shape neurodegeneration — and could be targeted therapeutically.
A landmark review reveals astrocytes as active immune players whose dysfunction drives Alzheimer's, Parkinson's, MS, and ALS.
Researchers propose a unified model classifying cancer-associated fibroblasts by molecular phenotype and spatial location to guide precision therapy.
AHA, ACC, ESC, and WHF release a landmark 2026 consensus redefining heart failure staging and classification worldwide.
A major Cell Metabolism review reveals how microbiome metabolites reprogram immune cells to drive or prevent cardiometabolic disease.
Semaglutide and liraglutide show promise for dry eye and corneal repair, but may cause periocular volume loss that affects blinking and tear distribution.
Machine learning and whole-genome sequencing may finally give doctors the tools to predict bacterial resistance before treatment fails.