DNA Mutation Clocks Reveal How Aging Drives Cancer Risk From Within
Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.
56 articles
Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.
A landmark review argues neurodegeneration is driven by interacting misfolded proteins, not single culprits โ reshaping diagnosis and treatment.
A landmark review maps the structural, genetic, and molecular changes that erode lung function with age โ and why reversing them matters.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
New research reveals how people over 100 maintain youthful immune systems despite chronic inflammation, offering insights for healthy aging.
A product review breaks down the evidence tiers for four popular longevity supplements and rates the best commercial stacks.
Dexcom G7 tops expert picks for metabolic biohacking, but evidence for non-diabetics remains mixed. Here's what the data says.
A landmark AHA statement challenges decades of blanket activity restrictions for children with cardiomyopathy, offering new risk-stratified guidance.
A new review reveals how epithelial-to-mesenchymal transition fuels tumor invasion, immune evasion, and drug resistance through dynamic, reversible states.
Expert reviews compare top CGMs for longevity use, but evidence for healthy adults remains limited. Here's what you need to know.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
A new framework proposes organ-specific biological clocks using multi-omics data to better predict disease onset and aging trajectories.