802 articles
Activating three Yamanaka factors — OCT4, SOX2, and KLF4 — appears to reverse epigenetic aging in human eye cells, marking a milestone in rejuvenation medicine.
Harvard longevity researcher David Sinclair argues that two nutritious meals daily meet caloric needs for sedentary workers — and flexible compensation beats rigid restriction.
Harvard longevity scientist David Sinclair makes the case that aging is the root cause of most disease and the true target of future medicine.
Peter Attia dissects the null results of the MET-PREVENT trial and what they reveal about the hard science of testing aging interventions.
USC researchers find young non-smokers with healthier diets face unexpected lung cancer risk, possibly due to pesticide residues on produce.
A 2-year human study links extra virgin olive oil to better cognition and gut diversity — and identifies the specific microbes responsible.
A JAMA Oncology study finds rising colorectal cancer deaths in adults under 50 are almost entirely concentrated in those without college degrees.
A 12-week trial finds morning people and night owls both gain more from workouts timed to their natural circadian rhythm.
The EV therapy pipeline is expanding rapidly, but standardization and clinical proof remain elusive challenges for this emerging field.
A phase III trial shows daraxonrasib doubled median survival in advanced pancreatic cancer, while gut bacteria may predict melanoma relapse risk.
A UK study of 17,000 patients found gabapentinoid users face nearly double the drug poisoning risk early in treatment, especially combined with opioids or benzodiazepines.
New French study finds low-dose aspirin reduces cardiovascular events in GCA patients but increases brain bleed risk at one year.
