6,382 articles
A 61-analyte, three-matrix metabolomics platform outperforms standard bile acid testing by exposing gut-liver dynamics that single-sample methods miss.
PBAE nanoparticles deliver two genes directly into scar tissue, converting astroglia into functional neurons and dissolving the scar barrier.
A mature phase III trial finds no survival difference between chemotherapy and radiotherapy as first-line treatment for low-grade glioma.
Adenosine 5'-monophosphate preserves muscle mass during sepsis by activating AMPK and blocking IL-1β, offering a potential new therapy.
New research reveals how defective newly-made proteins expose hidden molecular tags, triggering rapid cellular cleanup.
A mitochondrial sirtuin may hold the key to treating degenerative disc disease and the chronic low back pain it causes.
Plasma BDNF levels predict sarcopenia risk and detailed walking biomechanics in 646 older adults, illuminating the brain–muscle axis.
A large-scale digital trial tests whether LLM-generated, personalized coaching prompts can boost daily physical activity better than generic messages.
A novel injectable platform combining miR-197-3p and Prussian blue nanozymes reverses chondrocyte senescence and restores cartilage in OA models.
Johns Hopkins researchers reveal how TDP-43 loss accelerates toxic tau buildup, uncovering a key mechanism in Alzheimer's and related dementias.
A meta-analysis of 4 RCTs finds semaglutide and tirzepatide significantly reduce worsening heart failure events in obese patients within 5–6 months.
Imaging 16 million pancreatic cells reveals macrophage-T cell interactions and beta-cell stress signatures at the earliest, preclinical stages of type 1 diabetes.
