484 articles in this topic
A Dana-Farber/Broad Institute study links glioblastoma transcriptional states to survival outcomes in patients receiving immune checkpoint blockade.
A newly identified macrophage-Treg axis in tumor-draining lymph nodes may explain how colorectal cancer evades immune attack.
Cell publishes a tribute to Gregory J. Hannon, whose landmark work on RNAi and piRNA pathways reshaped cancer biology and gene regulation.
A newly discovered hepatic micropeptide suppresses liver cancer progression by jamming a key mitochondrial RNA processing complex.
New research reveals that whole-genome doubling triggers epigenetic changes that silence antigen presentation, letting tumors evade CD8+ T cells.
MIT researchers identify oncofetal cell states in colorectal tumors that mimic embryonic intestines and prime cancer cells for invasion.
A comprehensive review reveals how the senescence secretome suppresses tumors early but drives progression, resistance, and metastasis chronically.
Scientists discover that 3' UTRs of mRNAs actively guide protein folding during translation, controlling activity of key cancer and aging regulators.
A new commentary in Gut raises important concerns about using large language models to detect colorectal polyps in endoscopic images.
The BEGONIA trial finds durvalumab combined with trastuzumab deruxtecan achieves 62% response rate in hard-to-treat metastatic breast cancer.
Cancer cells that downregulate SMC4 enter a low-proliferation, diapause-like state that resists standard chemotherapy, revealing a dangerous survival mechanism.
A 260-organoid biobank reveals statins target chemoresistant pancreatic cancer by disrupting cholesterol and glycosylation pathways.
