290 articles in this topic
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
Knocking out BNIP3 in macrophages reduced adipose inflammation and improved insulin sensitivity in obese mice, revealing a new therapeutic target.
A 10-year MRI follow-up of two RCTs finds visceral fat reduction — not weight loss — drives lasting cardiometabolic protection.
New evidence reveals mitochondria form functionally distinct subpopulations within tissues and even single cells, reshaping how we understand energy metabolism.
New review reveals GLP-1 receptor agonists may directly suppress chronic inflammation across multiple organ systems, far beyond their metabolic benefits.
A noninvasive 13-variable score reveals how fast your liver is aging — and accelerated liver aging raises mortality risk by up to 85%.
A comprehensive review reveals how obesity and aging converge through shared inflammatory biomarkers, accelerating disease risk in the elderly.
New review reveals how popular weight-loss medications affect bone density and fracture risk — with some surprising findings.
A landmark JCI review maps the expanding pharmacological arsenal for MASH, from GLP-1 agonists to triple receptor therapies and precision medicine.
A systematic review of 8 studies finds tirzepatide significantly reduces hsCRP and IL-6 across all doses and populations.
A landmark Lancet review reveals GLP-1 receptor agonists protect the heart, kidneys, liver, and brain — reshaping how we think about metabolic medicine.
New research reveals how fatty liver disease reshapes the tumor microenvironment, potentially accelerating cancer metastasis.
