431 articles
A completed phase I trial tests regorafenib plus dual checkpoint inhibitors in 39 patients with hard-to-treat metastatic colorectal cancer.
A completed Phase 2 trial tests nivolumab plus ipilimumab in CDK12-mutant metastatic prostate and solid tumors across 56 patients.
A completed RCT tested whether a CBT-based smartphone app reduces moderate depression versus an active placebo in 158 participants; outcomes are not reported in the registration record.
A completed pilot trial tested humanoid robots and AI predictive models to manage dementia care at home, personalizing treatment pathways.
A Phase 2 pilot trial investigates whether the natural senolytic compound fisetin can reduce dysfunction and complications in COVID-19 patients.
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
A Phase 4 RCT tests whether one bevacizumab injection matches two combined doses for neovascular AMD outcomes over 12 months.
A completed RCT tests how water-based exercise at varying intensities affects blood pressure, sleep, mood, and function in elderly participants.
A completed trial tests whether internet-based CBT-I can reduce both insomnia severity and alcohol consumption in heavy-drinking adults.
A completed RCT from the University of Copenhagen tests whether aerobic exercise, time-restricted feeding, or NR supplementation best improves biological aging markers in healthy older adults.
A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.
A completed Phase II trial tests whether combining two checkpoint inhibitors can safely and effectively treat melanoma that has spread to the brain.
