First GWAS of Metformin Blood Levels Reveals Age, Kidney Function, and Ancestry Shape Drug Exposure
A 745-person genomic study identifies why metformin concentrations vary so widely — with ancestry-specific genetic variants playing a key role.
6,382 articles
A 745-person genomic study identifies why metformin concentrations vary so widely — with ancestry-specific genetic variants playing a key role.
Scientists engineer mammary organoids that secrete anticancer drugs while simultaneously regenerating functional breast tissue after surgery.
Japan's April 2026 revised guidelines now govern stem cell-based embryo models, marking a global regulatory milestone.
A biodegradable microneedle stent achieves sutureless intestinal anastomosis while releasing anti-inflammatory drugs triggered by local inflammation.
A precision CAR T cell therapy wipes out disease-driving myelofibrosis stem cells while sparing healthy ones — a potential cure candidate.
Science Translational Medicine publishes an erratum for a 2024 study on GDP-mannose and antitumor immunity in triple-negative breast cancer.
New research reveals hippocampal theta sweeps encode goal direction during navigation, offering clues to memory and spatial planning circuits.
New research links spinal cord tau pathology to tactile deficits and cognitive impairment in Alzheimer's via disrupted CCK neurons.
A correction to a landmark case-control study reexamines vitamin D's role in breast cancer risk among Saudi Arabian women.
New organoid research shows aged gut microbiota metabolites can directly induce aging changes in intestinal epithelium, pointing to microbiome as a key target.
A bile acid compound restores oocyte quality by activating a transcription factor that drives mitochondrial cleanup — offering a new target for fertility medicine.
A liver-specific protein triggers aging not through cell death, but by spreading senescence via mitochondrial dysfunction and inflammatory signals.