New Fat Cell Brake Discovered — Blocking IL-11 Boosts Calorie Burning in Obesity
Scientists identify IL-11 as a molecular brake on beige fat thermogenesis, and show blocking it improves metabolism in obese mice.
290 articles in this topic
Scientists identify IL-11 as a molecular brake on beige fat thermogenesis, and show blocking it improves metabolism in obese mice.
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
A rigorous MRI-based study finds that repeated hypoglycemia episodes leave brain glucose transport kinetics unchanged, challenging a leading hypothesis.
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.
A major Cochrane network meta-analysis protocol will rank all insulin regimens by efficacy and safety for adults with type 1 diabetes.
Landmark CKD trials enrolled mostly overweight patients — new evidence questions whether SGLT2 inhibitors work for lean, non-diabetic individuals.
A comprehensive review finds SGLT2 inhibitors reduce AKI risk in humans via hemodynamic, metabolic, and cellular protective pathways.
Wearable microneedle patches tap interstitial fluid to monitor glucose, lactate, and electrolytes in real time — no needles, no lab.
A novel conjugate merges GLP-1/GIP incretin signaling with pan-PPAR activation in one molecule, potentially revolutionizing metabolic therapy.
Super-resolution microscopy reveals how mitochondrial mRNAs are distributed, folded, and released during apoptosis inside living cells.
Early bile acid and incretin responses after duodeno-ileal diversion may forecast long-term glycaemic outcomes in metabolic disease.
Men with T2D showed significantly greater postural instability after exercising in humid heat, despite normal thermoregulatory responses.