6,382 articles
USP20 drives immune exhaustion in pancreatic cancer by hijacking cholesterol and autophagy — and blocking it triples treatment response in preclinical models.
A lipid metabolism enzyme called SMPD1 anchors the deadliest cancer mutation to the cell membrane — and blocking it may finally crack KRAS.
A large multicenter study finds GLP-1 receptor agonists dramatically outperform DPP-4 inhibitors in preventing HCC recurrence and death post-resection.
A flexible 3D crystal framework selectively traps xenon over krypton using temperature and the gas itself as triggers.
A century of twin data reveals women's educational attainment became steadily more heritable as Norway expanded opportunity and gender equality.
New satellite data reveals the SAA's radiation boundaries are more dynamic than thought, posing wider spacecraft risks.
Researchers silenced nearly every expressed gene in human iPSCs, creating a landmark map of pluripotency's genetic architecture.
A new prime editing approach gives scientists precise genetic control over filamentous fungi, opening the door to novel bioactive compounds.
Researchers improve ADAR-based RNA editing precision using guide RNAs modeled on highly edited natural substrates.
China is increasing prestigious funding for early-career researchers. Will it reduce the intense competition stifling scientific innovation?
Researchers discover LEF1 marks true self-renewing T cells in autoimmunity and chronic infection, opening new therapeutic targets.
Scientists uncover how corals repeatedly evolved a specialized organelle to house algal partners — by hijacking their own lysosomal machinery.
