Alzheimer's

446 articles in this topic

Vagus Nerve Stimulation Improves Quality of Life in Hard-to-Treat Depression
Brain Health

Vagus Nerve Stimulation Improves Quality of Life in Hard-to-Treat Depression

A year-long sham-controlled trial finds active VNS meaningfully improves daily function and quality of life in patients who failed 4+ antidepressants.

Research Paper
May 1, 2026 0
Retracted Alzheimer Study Flagged for Image Manipulation and Data Duplication
Brain Health

Retracted Alzheimer Study Flagged for Image Manipulation and Data Duplication

A 2018 paper on antileukotriene therapy and tau phosphorylation in Alzheimer's mice has been retracted due to image fraud.

Research Paper
May 1, 2026 0
Blood DNA Methylation Score Predicts Cognitive Ability and MCI Risk
Brain Health

Blood DNA Methylation Score Predicts Cognitive Ability and MCI Risk

MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.

Research Paper
May 1, 2026 0
Scientists Map the Brain Circuits That Trigger Epileptic Spikes Between Seizures
Brain Health

Scientists Map the Brain Circuits That Trigger Epileptic Spikes Between Seizures

Neuropixels recordings reveal how laminar microcircuits generate interictal epileptiform discharges โ€” and how to predict them 1 second in advance.

Research Paper
May 1, 2026 0
Brain Damage in Refractory Status Epilepticus Is 10x Worse Than Other Seizure Disorders
Brain Health

Brain Damage in Refractory Status Epilepticus Is 10x Worse Than Other Seizure Disorders

NfL biomarker levels in NORSE patients were 10-fold higher in CSF and 4-fold higher in serum than other seizure disorders, signaling massive neuroaxonal injury.

Research Paper
May 1, 2026 0
Intranasal Insulin Reverses Memory Loss and Brain Inflammation in Aging Mouse Model
Brain Health

Intranasal Insulin Reverses Memory Loss and Brain Inflammation in Aging Mouse Model

A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.

Research Paper
Apr 30, 2026 0
Amyloid Immunotherapy for Alzheimer's Faces a Critical Interpretation Problem
Brain Health

Amyloid Immunotherapy for Alzheimer's Faces a Critical Interpretation Problem

Leading neurologists argue that amyloid aggregation dynamics may be distorting how we read clinical trial results for Alzheimer's immunotherapies.

Research Paper
Apr 30, 2026 0
AI Algorithm Uncovers Distinct Alzheimer's Subtypes Hidden in Brain Omics Data
Brain Health

AI Algorithm Uncovers Distinct Alzheimer's Subtypes Hidden in Brain Omics Data

A multi-omics subspace-merging algorithm identifies biologically distinct AD subtypes, pointing toward personalized treatment strategies.

Research Paper
Apr 30, 2026 0
Scientists Discover Brain Switch That Controls Access to Old vs New Memories
Brain Health

Scientists Discover Brain Switch That Controls Access to Old vs New Memories

A newly identified GABAergic pathway in mice lets the brain toggle between updated and previous memories โ€” a key insight for memory disorders.

Research Paper
Apr 30, 2026 0
Harvard Maps the Mouse Nose to Reveal How Social Smells Are Decoded
Brain Health

Harvard Maps the Mouse Nose to Reveal How Social Smells Are Decoded

A molecular atlas of the mouse olfactory system reveals how social odor signals are spatially organized from nose to brain.

Research Paper
Apr 30, 2026 0
Alpha-Synuclein Biomarkers Could Transform Early Parkinson's Diagnosis
Brain Health

Alpha-Synuclein Biomarkers Could Transform Early Parkinson's Diagnosis

New review maps how ฮฑ-synuclein assays may detect Parkinson's before symptoms appear โ€” and what stands between lab and clinic.

Research Paper
Apr 29, 2026 0
Astrocytes Drive Stroke Brain Damage Through Oxidative Stress and Collagen Buildup
Brain Health

Astrocytes Drive Stroke Brain Damage Through Oxidative Stress and Collagen Buildup

A new Cell Metabolism study reveals how oxidative stress triggers astrocytes to produce collagen, forming barriers that kill neurons after stroke.

Research Paper
Apr 29, 2026 0
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