Cancer Research
New Mechanism Found That Could Reverse Drug Resistance in Colorectal Cancer
Scientists identify how the HMBOX1-HACE1-ATG5 axis suppresses autophagy to restore 5-FU chemosensitivity in colorectal cancer.
Research Paper
May 21, 2026 0
Cancer
484 articles in this topic
Cancer Research
Dormant Breast Cancer Cells Slashed 80–87% by Repurposed Drugs in Phase 2 Trial
A randomized trial shows hydroxychloroquine and everolimus can dramatically reduce dormant tumor cells in breast cancer survivors, potentially preventing relapse.
Research Paper
May 21, 2026 0
Cancer Research
Metabolic Enzyme DLAT Hijacks Leucine Breakdown to Fuel Liver Cancer Growth
A pyruvate metabolism enzyme suppresses leucine catabolism to keep mTOR active in liver cancer — and blocking it shrinks tumors in vivo.
Research Paper
May 21, 2026 0
Cancer Research
Personalized DNA Vaccine Triggers Immune Response in Deadly Brain Cancer
A bespoke DNA vaccine tailored to individual glioblastoma tumors shows promising immunological activity in one of oncology's hardest challenges.
Research Paper
May 21, 2026 0
Cancer Research
Common Asthma Drug Target May Unlock Stalled Cancer Immunotherapy
Blocking CysLTR1 reprograms immunosuppressive neutrophils and reverses resistance to anti-PD1 checkpoint therapy in mice.
Research Paper
May 21, 2026 0
Cancer Research
Lipid Molecule 12-HETE Found to Cripple Immune Cells in Liver Cancer
A newly identified lipid mediator may explain why immune cells fail to fight MASH-driven liver cancer, opening therapeutic targets.
Research Paper
May 21, 2026 0
Cancer Research
Immune Cells May Shield Lynch Syndrome Patients From Colorectal Cancer
MAIT cells appear to provide protective immune surveillance in Lynch syndrome carriers who haven't developed colorectal cancer, suggesting new risk stratification tools.
Research Paper
May 21, 2026 0
Cancer Research
Personalized Medicine Is Reshaping How We Treat the Deadliest Ovarian Cancer
A comprehensive review in CA Cancer J Clin maps the molecular biology, treatment strategies, and equity gaps in high-grade serous ovarian cancer.
Research Paper
May 20, 2026 0
Cancer Research
Tumors Evolve Hidden Escape Routes That Dodge Immune Attack in Lung Cancer
New research reveals how lung cancer subclones develop distinct immune evasion strategies, complicating immunotherapy response.
Research Paper
May 20, 2026 0
Cancer Research
Why Cushing's Tumors Stop Responding to Temozolomide
New research reveals how corticotroph pituitary tumors develop resistance to temozolomide through clonal selection of high MGMT-expressing cells.
Research Paper
May 19, 2026 0
Cancer Research
Radiation Therapy Rivals Surgery for Early-Stage Liver Cancer in Largest Study Yet
A multinational study of 4,913 patients finds EBRT delivers survival outcomes comparable to surgery and ablation for early hepatocellular carcinoma.
Research Paper
May 19, 2026 0
Cancer Research
Radiation to Metastases Cuts Cancer Progression Risk in Half in Phase II Trial
Adding targeted radiation to standard therapy reduced progression by 46% across multiple cancer types in the EXTEND trial.
Research Paper
May 19, 2026 0