Harvard Finds Gut Bacteria Fuel Depression by Triggering Hidden Inflammation
A gut microbe converts a common pollutant into an inflammation trigger linked to depression, revealing a new molecular pathway.
20 articles
A gut microbe converts a common pollutant into an inflammation trigger linked to depression, revealing a new molecular pathway.
Scientists discover harmful bacterial sugars in the gut trigger immune attacks that damage the brain in ALS and dementia patients.
Common respiratory bacterium persists in retinas and brains, triggering inflammation and amyloid buildup linked to cognitive decline.
A molecule called OLE restores microglia's protective function, reducing amyloid plaques and improving memory in animal models.
A 12-week clinical trial found older adults taking probiotics with antidepressants had greater reductions in depression and anxiety than placebo.
Researchers discover TMEM175, a cellular safeguard that prevents toxic buildup linked to Parkinson's when it malfunctions.
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
Arginine supplements reduced toxic amyloid buildup, brain inflammation, and behavioral decline in fly and mouse Alzheimer's models.
A landmark study links epigenetic patterns at birth to infant gut microbiome development, with certain bacteria reducing neurodevelopmental risk by age three.
New MRI technology reveals a previously unknown waste-removal pathway in the human brain that could transform how we treat neurodegenerative diseases.
Researchers restored a key brain circuit in mice and reversed anxiety and social withdrawal, pointing to a powerful new therapeutic target.
Buck Institute finds the longevity-linked APOE2 variant shields neurons from DNA damage and cellular senescence, explaining its Alzheimer's protection.
New research reveals how brain immune cells destroy smell-related nerve connections in early Alzheimer's, offering hope for earlier detection.
Researchers turned ordinary brain cells into plaque-clearing machines, reducing Alzheimer's amyloid by half in mice with one treatment.
Declining Menin in the hypothalamus drives inflammation and aging. Restoring it reversed decline; D-serine amino acid improved cognition in mice.
Researchers finally discovered lecanemab activates brain immune cells through a specific antibody fragment to clear toxic plaques.
UC Riverside researchers show amyloid beta may displace tau from neurons, triggering brain cell breakdown before plaques even form.
Raising Sox9 levels in aging astrocytes reduced amyloid plaque buildup and protected memory in mouse models with existing Alzheimer's symptoms.
A new tool that boosts mitochondrial activity in neurons restored memory in dementia mice, suggesting energy failure drives Alzheimer's symptoms.
Researchers finally discovered how lecanemab clears brain plaques by activating immune cells through a specific antibody fragment.