20 articles
A completed trial investigates whether replenishing glutathione precursors can reverse metabolic dysfunction in elderly adults.
Swiss researchers studied how mTOR protein in fat tissue affects metabolism and insulin function throughout the body.
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
Columbia University tested whether the diabetes drug metformin could slow memory loss in people with mild cognitive impairment.
UCSF study reveals how metformin and trimethoprim interfere with thiamine uptake, potentially affecting energy metabolism.
A Danish case-control trial uses gold-standard metabolic testing to uncover how mtDNA mutations impair muscle glucose uptake and drive insulin resistance.
Small trial tested whether the diabetes drug metformin could enhance immune response to pneumonia vaccine in aging adults.
Wake Forest study explores whether the diabetes drug metformin can trigger cellular changes linked to longevity in healthy people.
Carmot Therapeutics tests CT-868, a novel dual incretin receptor agonist, for HbA1c reduction in overweight and obese adults with poorly controlled T2DM.
Clinical trial tested whether metformin could improve surgical outcomes and reduce hospital stays in non-diabetic older patients.
Study reveals how lean people can still have obesity-like metabolism and whether calorie restriction helps reverse this dangerous condition.
Takeda's Phase 1 trial evaluates the safety and tolerability of TAK-510, a novel injectable agent targeting nausea and vomiting, across escalating doses.
A completed University of Michigan trial explored how aerobic exercise training alters RAGE-mediated inflammatory pathways in type 2 diabetic adults.
Small trial tests whether diabetes drug metformin can enhance immune response to flu vaccination in aging adults.
Phase 4 trial tests whether alirocumab can better control non-HDL cholesterol in high-risk type 2 diabetics failing statin therapy.
Clinical trial tested whether metformin could enhance resistance training benefits for muscle mass and strength in older adults.
Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.
University of Pennsylvania study tests behavioral tools to help people stick with time-restricted eating for blood pressure and weight management.
Major trial tests whether diabetes drug metformin can prevent frailty syndrome that affects millions of aging adults.
A completed Maastricht trial tests whether targeted protein and exercise can boost muscle protein synthesis before dialysis becomes necessary.
