20 articles
Transcriptomic analysis of Pseudomonas nitroreducens TX1 identifies 241 differentially expressed genes during surfactant degradation.
Scientists identify MOXD1 as a driver of MASH and show blocking it with a small molecule reverses liver fat accumulation in mice.
Simple sugar supplement dramatically improved diabetes symptoms in mice by stopping inflammatory cells from releasing disease-causing particles.
Knocking out BNIP3 in macrophages reduced adipose inflammation and improved insulin sensitivity in obese mice, revealing a new therapeutic target.
Two bacterial proteins that sense sulfur compounds unexpectedly regulate nitrate removal, revealing new targets for optimizing wastewater treatment.
New research shows dietary methionine enhances kidney function to clear harmful inflammatory molecules from the bloodstream.
Scientists discover breath analysis can instantly detect gut bacteria composition, opening new paths for microbiome diagnostics.
New research reveals how gut bacteria, toxic fats, and immune responses create parallel inflammatory attacks on the liver.
Scientists identify an NADH-dependent molecular switch linking glycolysis to mitochondrial ATP synthesis, revealing a new metabolic control point.
Large study reveals how gut microbe proteins shift with aging and contribute to diabetes and metabolic disorders.
New research validates high-throughput methods for studying mitochondrial dysfunction in malignant hyperthermia susceptibility.
Natural polyketide from marine bacteria enhances cholesterol removal and improves fat metabolism in liver cells and mice.
New research reveals how glucose metabolism directly controls fat tissue expansion through a novel epigenetic pathway involving JMJD1A.
New research reveals how psoriasis increases inflammatory bowel disease risk by disrupting intestinal fat metabolism through immune cells.
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
A novel conjugate merges GLP-1/GIP incretin signaling with pan-PPAR activation in one molecule, potentially revolutionizing metabolic therapy.
Combined mitochondrial therapy restored muscle function and reduced fatigue in mouse model of Gulf War Illness.
A landmark JCI review maps the expanding pharmacological arsenal for MASH, from GLP-1 agonists to triple receptor therapies and precision medicine.
New research reveals how RAP1A protein regulates liver blood vessel function and may influence fibrosis progression in chronic liver disease.
Researchers discover unique molecular patterns in lipedema patients and develop predictive models for this poorly understood condition affecting women.
