20 articles
AI-driven study identifies ฮฑ-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.
A comprehensive review examines how marine-derived bioactives like omega-3s, astaxanthin, and polysaccharides may combat chronic neuroinflammation underlying major neurodegenerative diseases.
A 3-month fish hydrolysate supplement significantly improved episodic memory in healthy seniors showing accelerated cognitive decline, with reduced inflammation markers.
AAV delivery of AIBP protein restores cholesterol balance, silences inflammation, and preserves vision in glaucoma models.
DPCPX treatment enhanced neurogenesis and improved motor/memory function in stroke recovery studies using advanced PET imaging.
A naturally occurring fatty acid amide activates immune cells in the retina, protecting neurons and blood vessels from degenerative damage.
Synthetic peptide chimeras degrade amyloid-beta across the blood-brain barrier, improving cognition in mice with fewer risks than current immunotherapies.
A phase 2 RCT finds ABvac40, a vaccine targeting vascular amyloid-ฮฒ40, is safe and immunogenic in early Alzheimer's patients with no ARIA-E.
New research reveals capsaicin from chili peppers improves brain health by altering gut bacteria and cholesterol metabolism.
Gut metabolite urolithin A dramatically reduced anxiety in rodent models by fixing mitochondrial dysfunction in brain reward circuits.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
A novel brain organoid stress model reveals how combining walnut peptide and theanine activates BDNF pathways to reduce anxiety and boost cognition.
Researchers discover a phospholipid derivative that protects brain cells by calming overactive immune cells in dementia-prone mice.
A lab study finds ACU193 binds less to brain blood vessels than lecanemab, potentially explaining differences in ARIA side effect risk.
27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.
Cryo-EM reveals VPS13A and scramblase XK work together to ferry lipids across organelle contact sites, unlocking a fundamental cell biology mystery.
Emerging mycotoxin found in foods crosses blood-brain barrier, disrupts neurotransmitters and impairs cognitive function in animal model.
SOMCL-668 improved memory and reduced brain damage in Alzheimer's mice by targeting sigma-1 receptors and protective pathways.
Overexpressing Sox9 in brain support cells triggers plaque cleanup and protects cognition in Alzheimer's mouse models.
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
