20 articles
Astellas reports encouraging early-stage results for a stem cell-derived treatment targeting age-related eye disease, though data remains limited.
AstraZeneca's baxdrostat wins FDA approval for hypertension, offering a novel mechanism for patients uncontrolled on existing therapies.
Single-cell sequencing reveals ferroptosis drives pulpitis; thymosin ฮฑ1 restores GPX4, cuts iron overload, and reduces inflammation in cells and rats.
Revolution Medicines' RAS inhibitor daraxonrasib shows breakthrough results in pancreatic cancer, doubling patient survival times.
Mitochondria-targeted antioxidant polymer shows superior protection against liver transplant injury compared to standard treatments.
New research reveals umbilical cord and fat-derived exosomes target different aspects of skin aging with complementary effects.
First successful gene therapy for aniridia increases retinal thickness and activates key vision pathways in mice.
New review reveals how exosomes could revolutionize skin cancer treatment by delivering drugs directly to tumors while reducing side effects.
Novel nanogel therapy targets mitochondrial ROS to break the inflammation-hypoxia cycle in periodontitis, showing strong preclinical results.
A novel photoactivatable drug system uses NK immune cells to eliminate aging joint cells, reducing osteoarthritis progression in mice.
Scientists use lipid nanoparticles to correct genetic mutations causing severe skin disorders, restoring 30% of normal protein function.
The transcription factor Lhx2 in liver stellate cells promotes regeneration and suppresses fibrosis via TGF-ฮฒ and HGF pathways.
Scientists discover non-canonical muscle stem cells in zebrafish and axolotls that could unlock new regenerative therapies for humans.
Injectable hydrogel from traditional Chinese herbs shows superior wound repair by regulating immune response and promoting tissue regeneration.
Scientists decode how axolotl digits regrow, uncovering unique mechanisms that could revolutionize regenerative medicine.
AAV gene therapy successfully restored retinal function and improved vision in rats with LRAT-associated retinitis pigmentosa.
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Researchers identify how host macrophages destroy foreign cells in embryos โ and three strategies to stop it, boosting organ-growing chimeras.
Phase 3 data show exa-cel eliminated transfusions and vaso-occlusive crises in children ages 5โ11 with serious inherited blood disorders.
Tiny cellular vesicles called exosomes could revolutionize treatment for eye cancers and help regenerate damaged vision.
