Pfizer's PCSK9 Inhibitor Bococizumab Put to the Test in High-Risk Hyperlipidemia
A Phase 3 trial examines whether bococizumab slashes LDL in statin-treated patients at elevated cardiovascular risk.
20 articles
A Phase 3 trial examines whether bococizumab slashes LDL in statin-treated patients at elevated cardiovascular risk.
A first-in-human Phase 1 trial evaluates PF-07257876, a dual-checkpoint bispecific antibody targeting both CD47 and PD-L1, in hard-to-treat cancers.
Phase 3 trial of IBI306, a PCSK9 inhibitor, tests LDL-C reduction in Chinese adults with high cardiovascular risk on statin therapy.
Phase 1 trial of acapatamab, a PSMA-targeting bispecific T-cell engager, enrolls 212 men with metastatic castration-resistant prostate cancer.
A completed RCT tests whether adding collagen peptides to standard calcium and vitamin D supplementation improves bone density and remodeling markers in women with osteopenia.
Pfizer's first-in-human trial of PF-07209960, a dual-action immunotherapy fusion protein, was terminated after enrolling 37 patients.
12-month trial examined whether oral MK-677 could restore youthful growth hormone levels and improve body composition in healthy seniors.
150-person trial tests whether PRP injections can reduce knee pain and improve function better than placebo in osteoarthritis patients.
A first-in-human multiple-ascending-dose trial tests Contraloid, an oral peptide designed to disassemble toxic amyloid-beta oligomers linked to Alzheimer's disease.
Military study tests regenerative PRP injections against placebo for facet joint pain in 91 participants.
Small trial tests hormone-based therapy to combat age-related muscle and bone loss in vulnerable adults.
University study tests whether collagen peptides combined with exercise improve muscle mass, bone health, and quality of life in older adults.
Adipose-derived stem cells combined with platelet-rich plasma evaluated for treating moderate to severe knee osteoarthritis over 2 years.
A completed multicenter feasibility trial evaluates BTM, a novel biodegradable scaffold, for treating serious deep burn injuries.
Contraloid acetate, an oral all-D-peptide designed to disassemble toxic amyloid-beta oligomers, completed its first-in-human safety trial in 40 healthy volunteers.
A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.
A completed Phase IIIb trial tests whether pelacarsen can safely lower Lp(a) in historically underrepresented cardiovascular disease populations.
Autologous stem cell injections tested in patients with severe leg circulation problems who had no surgical options.
Pfizer's 24-month study of oral growth hormone secretagogue CP-424,391 in 396 at-risk elderly adults was terminated early.
Clinical trial tests platelet-rich plasma therapy for shoulder osteoarthritis in 91 patients over 5 months.