Herbal Compound Clears Alzheimer's Plaques by Activating AMPK Autophagy Pathway
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
20 articles
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
Italian researchers test plant-based compounds for brain health and quality of life in aging adults with promising early results.
AI-driven study identifies α-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.
A completed trial tests whether daily Nordic berry beverages can sharpen cognition in healthy adults over 12 weeks.
New research shows Hericium erinaceus can force neuroblastoma cells to differentiate into mature neurons while stopping their cancerous growth.
Single-cell analysis reveals how the flavonoid fisetin may reduce neuroinflammation in Alzheimer's disease by targeting specific astrocyte subgroups.
Pomegranate metabolite urolithin A reduced brain damage and improved recovery in mouse stroke model by blocking inflammation and cell death.
The EPICURO trial tests MERIVA® turmeric over 6 months to see if it protects cognition in adults with metabolic syndrome.
A novel brain organoid stress model reveals how combining walnut peptide and theanine activates BDNF pathways to reduce anxiety and boost cognition.
A 4-week pilot trial finds nicotinamide riboside boosts cerebrovascular response and cognitive performance in older adults with peripheral artery disease.
Probucol, a discontinued cholesterol medication, may boost brain-protective proteins in older adults at risk for dementia.
Gut metabolite urolithin A dramatically reduced anxiety in rodent models by fixing mitochondrial dysfunction in brain reward circuits.
Systematic review reveals lithium may slow amyloid buildup and tau protein damage in Alzheimer's disease models.
Leading OB/GYN reveals why PCOS and endometriosis often go undiagnosed and shares evidence-based treatments for women's hormone health.
27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.
A completed Phase 4 trial from India evaluates whether ALA supplementation boosts flunarizine's migraine-prevention power in adolescents.
24-week trial tested fucoxanthin-rich microalgae supplement on memory, attention, and executive function in 66 healthy seniors.
β-endorphin released during exercise wraps around toxic Aβ aggregates, forming a 'corona' that shields brain cells from Alzheimer's damage.
A completed trial tests EGCG combined with diet, exercise, and cognitive training to slow decline in ApoE4 carriers with early warning signs.
Scientists develop pathway-selective drug that activates beneficial brain receptors while avoiding negative feedback loops.