Herbal Compound Clears Alzheimer's Plaques by Activating AMPK Autophagy Pathway
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
20 articles
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
AI-driven study identifies ฮฑ-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.
New research shows Hericium erinaceus can force neuroblastoma cells to differentiate into mature neurons while stopping their cancerous growth.
Single-cell analysis reveals how the flavonoid fisetin may reduce neuroinflammation in Alzheimer's disease by targeting specific astrocyte subgroups.
Pomegranate metabolite urolithin A reduced brain damage and improved recovery in mouse stroke model by blocking inflammation and cell death.
A novel brain organoid stress model reveals how combining walnut peptide and theanine activates BDNF pathways to reduce anxiety and boost cognition.
A 4-week pilot trial finds nicotinamide riboside boosts cerebrovascular response and cognitive performance in older adults with peripheral artery disease.
Gut metabolite urolithin A dramatically reduced anxiety in rodent models by fixing mitochondrial dysfunction in brain reward circuits.
Systematic review reveals lithium may slow amyloid buildup and tau protein damage in Alzheimer's disease models.
27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.
ฮฒ-endorphin released during exercise wraps around toxic Aฮฒ aggregates, forming a 'corona' that shields brain cells from Alzheimer's damage.
Scientists develop pathway-selective drug that activates beneficial brain receptors while avoiding negative feedback loops.
Comprehensive review examines curcumin, ginkgo, nootropics, and brain stimulation techniques for improving memory and focus.
Scientists identify ferroptosis as a key driver of Alzheimer's disease, opening doors to iron-based prevention therapies.
New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Review reveals how PQQ supplement protects neurons via antioxidant, mitochondrial, and anti-inflammatory mechanisms in neurodegenerative diseases.
New research maps a stress-signaling cascade linking p53 activation to brain inflammation and depression, with curcumin interrupting it.
Comprehensive review reveals B6, B9, and B12 vitamins demonstrate promising effects in Alzheimer's clinical trials.
Combining psilocybin with D-serine or D-cycloserine dramatically reduced hallucinogenic effects while enhancing neuroplasticity markers in mice.