20 articles
Daily anthocyanin supplementation helped over half of prediabetic participants return to normal glucose tolerance in just 12 weeks.
New research reveals how the cholesterol medication bempedoic acid directly activates PPARΞ±, boosting fat metabolism beyond its known effects.
Ketone body Ξ²-OHB prevents sepsis-induced liver damage by modifying antioxidant enzyme SOD2, offering new therapeutic approach.
UCSF study reveals how metformin and trimethoprim interfere with thiamine uptake, potentially affecting energy metabolism.
A steroid hormone activates receptor GPR56 to block ferroptosis, a form of iron-driven cell death linked to liver disease.
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
Natural polyketide from marine bacteria enhances cholesterol removal and improves fat metabolism in liver cells and mice.
NIH study identifies metabolic mechanism behind controversial skin condition and demonstrates successful treatment with mitochondrial complex I inhibitors.
New research shows phosphatidylserine supplementation reduces liver fat and inflammation while improving glucose control through enhanced fat metabolism.
A landmark RCT shows finerenone reduces eGFR decline and kidney-cardiovascular events in CKD patients without diabetes.
Master the advanced molecular architecture of AMPK β from isoform-specific signaling and spatial compartmentalization to emerging pharmacological strategies targeting the energy sensor at the heart of longevity biology.
Experimental diabetes drug IC7Fc reduces cholesterol and artery plaque buildup, offering cardiovascular benefits even without weight loss.
Scientists discover vitamin B3 can target a key genetic driver of fatty liver disease, offering hope for 30% of people affected globally.
New research shows acupuncture significantly reduces insulin resistance and hormone imbalances in PCOS by targeting bile acid pathways.
HDM1002, an oral GLP-1 receptor agonist, achieved significant weight loss with manageable side effects in overweight Chinese adults.
A newly identified protein shields the liver from alcohol injury by bridging mitochondria and fat droplets to enhance fatty acid oxidation.
Scientists discover vitamin B3 can target a key genetic driver of fatty liver disease, offering hope for a safe, accessible treatment.
Baxdrostat becomes the first-in-class aldosterone synthase inhibitor approved to treat resistant hypertension alongside existing drugs.
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
Simple sugar supplement dramatically improved diabetes symptoms in mice by stopping inflammatory cells from releasing disease-causing particles.
