Common Medications May Block Vitamin B1 Absorption in Small Clinical Trial
UCSF study reveals how metformin and trimethoprim interfere with thiamine uptake, potentially affecting energy metabolism.
20 articles
UCSF study reveals how metformin and trimethoprim interfere with thiamine uptake, potentially affecting energy metabolism.
Wake Forest study explores whether the diabetes drug metformin can trigger cellular changes linked to longevity in healthy people.
Mediterranean diet, resistance training, and diabetes medication combined to combat sarcopenia and improve metabolic health in older adults.
Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.
Four-year study examined whether metformin could protect blood vessels in people with metabolic syndrome beyond its diabetes benefits.
A sponsored 90-day trial of enhanced-absorption quercetin targeting cholesterol, blood sugar, and metabolic age was terminated before completion.
Columbia University tested whether the diabetes drug metformin could slow memory loss in people with mild cognitive impairment.
275-patient study tests novel liver-targeted therapy for NASH, a serious form of fatty liver disease affecting millions worldwide.
84-person study reveals how targeted nutrition counseling impacts blood sugar, weight, and heart health in diabetic patients.
A Phase 2 trial tests a GalNAc-conjugated antisense therapy in familial partial lipodystrophy patients with dangerously high triglycerides.
Major trial tests whether diabetes drug metformin can prevent frailty syndrome that affects millions of aging adults.
176-person trial tested whether pioglitazone could improve liver health by targeting insulin resistance in patients with fatty liver disease.
New study reveals metformin's anti-aging effects depend entirely on whether you're insulin resistant or sensitive.
A completed University of Michigan trial explored how aerobic exercise training alters RAGE-mediated inflammatory pathways in type 2 diabetic adults.
12-week controlled feeding study tests whether eating more whole fruit can improve blood sugar control and potentially reverse diabetes.
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
Carmot Therapeutics tests CT-868, a novel dual incretin receptor agonist, for HbA1c reduction in overweight and obese adults with poorly controlled T2DM.
Phase 4 trial tests whether alirocumab can better control non-HDL cholesterol in high-risk type 2 diabetics failing statin therapy.
Small trial tested whether the diabetes drug metformin could enhance immune response to pneumonia vaccine in aging adults.
Small study tests whether combining Mediterranean eating, intermittent fasting, and exercise can reverse diabetes in 6 months.