Grape-Derived Compound PCC1 Clears Senescent Cells to Heal Diabetic Wounds
ProcyanidinC1, a natural senolytic, selectively eliminates senescent cells in diabetic skin, dramatically improving wound healing in mouse models.
20 articles
ProcyanidinC1, a natural senolytic, selectively eliminates senescent cells in diabetic skin, dramatically improving wound healing in mouse models.
Scientists discover how plant compounds enhance stem cell therapy for kidney disease through improved cellular messaging.
A sweeping review maps every known strategy for delivering therapies directly to mitochondria, from lifestyle habits to nanocarriers and gene editing.
Injectable hydrogel from traditional Chinese herbs shows superior wound repair by regulating immune response and promoting tissue regeneration.
BIIB080 failed its primary endpoint in Phase 2, yet Biogen sees potential signals worth pursuing in the fight against Alzheimer's tau tangles.
New review reveals how plant-based compounds and stem cell therapies could eliminate aging cells and restore youthful function.
Novel iodide-enhanced hydrogel penetrates gum pockets to eliminate harmful bacteria while protecting regenerative stem cells.
Breakthrough prodrug technology enables oral delivery of allopregnanolone, showing promise for treating anxiety and mood disorders.
Researchers used AI screening to identify bavisant, a histamine receptor drug, as a potential therapy to repair nerve damage in MS.
Blocking the AhR receptor promotes axon regeneration and functional recovery in spinal cord and peripheral nerve injuries.
PARP inhibitors have transformed cancer treatment, but resistance and toxicity are emerging as serious limits to their long-term effectiveness.
New hydrogel combining copper ions with plant compound dramatically improves diabetic wound healing in mice studies.
Discover how revolutionary drugs target 'zombie cells' that accumulate with age, potentially reversing aging and extending healthspan.
A new wave of antidepressants is targeting patients who don't respond to standard treatments, with implications for brain health and longevity.
MSC-derived exosomes delivered via ear injection protect vestibular hair cells, cut apoptosis, and boost autophagy better than dexamethasone.
Bacteriophages could offer a breakthrough solution to combat the growing crisis of antibiotic-resistant infections threatening global health.
Clinical trial investigated whether pressurized oxygen treatments could stimulate new blood vessel growth in elderly participants.
Scientists discover how tumors use glucose to survive lysosome-blocking drugs, revealing promising combination therapies.
AstraZeneca's baxdrostat wins FDA approval for hypertension, offering a novel mechanism for patients uncontrolled on existing therapies.
A senolytic pairing of dasatinib and quercetin cleared senescent cells at the tendon-bone junction, dramatically improving repair strength in aged rats.