20 articles
An oral iron-targeting drug significantly slowed Multiple System Atrophy progression in a Phase 2 trial, with Phase 3 planning underway.
Bepirovirsen, an antisense oligonucleotide, delivered functional cures in ~20% of chronic hepatitis B patients — a landmark leap over existing therapies.
Diranersen reduced tau biomarkers and slowed cognitive decline in early Alzheimer's patients, marking a milestone for tau-directed therapy.
ATX-304 raised resting metabolic rate 8%, slashed triglycerides, and reduced liver fat in an 8-week Phase 1b trial for prediabetes.
New Brazilian baru nuts show promise for lowering cholesterol, but regular almonds may deliver superior results at lower doses.
A phase III trial shows saroglitazar helped 57% of primary biliary cholangitis patients achieve biochemical response vs just 10% on placebo.
Cambrian Bio's ATX-304 reduced liver fat, visceral fat, and raised resting metabolic rate by 8% in a Phase 1b trial of adults with prediabetes.
Simple supplement combination showed dramatic reductions in glioblastoma tumor markers without side effects in 10-patient trial.
A 24-year-old took tejocote root pills and nearly died. The culprit: toxic yellow oleander hidden in mislabeled supplements.
Cambrian Bio's ATX-304 combines AMPK and mitochondrial activation in a pill form, with Phase 1b data in prediabetic obese adults due this week.
Baxdrostat blocks aldosterone production directly, cutting systolic BP by ~15 mmHg in resistant hypertension patients who failed other drugs.
Rubedo's RLS-1496 reduced actinic keratosis lesions by 46% in four weeks with minimal side effects, targeting aging cells behind the damage.
Montara Therapeutics wins MJFF funding to activate brain autophagy using mTOR inhibitors — without dangerous whole-body side effects.
Seragon's oral combo therapy SRN-901 outperforms rapamycin in mice, boosting lifespan and slashing frailty through multi-pathway aging intervention.
Fisetin is emerging as a top senolytic candidate, clearing senescent cells linked to aging — and strawberries are its richest dietary source.
New neurology findings link psilocybin to Alzheimer's improvements and hearing aid use to lower dementia risk across 33 countries.
A copper compound restored brain waste-clearance pumps, cutting toxic amyloid buildup by 42% and improving spatial memory by 44% in preclinical tests.
A quercetin, NR, urolithin A, and alpha-lipoic acid combination boosted remaining lifespan in aged mice by 33%, even on a Western diet.
Bemnifosbuvir blocks hepatitis E replication in lab tests, offering hope for treating a virus that kills 70,000 people annually.
A Stanford trial finds combining buprenorphine with ketamine nearly doubles the reduction in suicidal ideation scores over 31 days.
