Epigenetic Clocks Predict Alzheimer's Biomarker Changes 15 Years in Advance
Study of 2,366 women shows biological aging markers predict future increases in tau, amyloid, and neuroinflammation proteins linked to dementia.
20 articles
Study of 2,366 women shows biological aging markers predict future increases in tau, amyloid, and neuroinflammation proteins linked to dementia.
DNA methylation biomarkers from a simple blood test may track cognitive aging and neurological disease risk with unprecedented precision.
New AI model using blood tests better predicts brain aging and amyloid buildup linked to dementia risk.
Study of 833 people finds depression linked to premature biological aging in both brain structure and DNA methylation patterns.
New research links age at Parkinson's onset and family history to the likelihood of carrying disease-causing genetic variants.
New p-tau217 blood test forecasts Alzheimer's symptoms within 3-4 years, potentially revolutionizing early intervention strategies.
In CADASIL patients, MRI-derived brain age runs years ahead of chronological age, tracking disease severity and cognitive decline.
Stanford researcher reveals how exercise, fasting, and sunlight trigger youthful blood proteins that rejuvenate aging organs.
New Nature Medicine research links harmful physical and social exposures to accelerated brain aging, with major implications for dementia prevention.
Stanford researcher reveals how proteins in young blood can rejuvenate aging brains and improve cognition.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
Plasma p-tau217 accurately detects preclinical Alzheimer's in cognitively normal adults, potentially enabling earlier intervention.
Revolutionary biofluid markers can identify neurodegenerative diseases early through simple blood tests, transforming prevention.
A streamlined mass spectrometry assay detects preclinical Alzheimer's from just 100 ยตL of blood with AUC 0.81 vs 0.65 for previous methods.
Scientists discover that subtle changes in blood protein structure can identify Alzheimer's earlier than current tests.
A global consortium reveals how tube type, delays, and storage temperature dramatically skew key Alzheimer's blood biomarker readings.
Researchers develop 98% accurate plasma protein panel that detects ALS disease process years before clinical onset.
New molecular mapping technique identifies individuals uniquely and predicts cognitive decline more accurately than standard brain scans.
Researchers at Duke University tested a blood-based biomarker to stratify Alzheimer's patients from healthy adults, aiming to enable earlier detection.
A 4-protein panel in neuronal extracellular vesicles outperforms standard plasma tests in flagging early Alzheimer's brain changes.